Evidence map›Paper›PMID 33119471›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2021

Altered airway mechanics in the context of obesity and asthma.

Jason H T Bates, Ubong Peters, Nirav Daphtary, Erick S MacLean, Kevin Hodgdon, David A Kaminsky, Swati Bhatawadekar, Anne E Dixon

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Mechanical ventilation energy analysis: Recruitment focuses injurious power in the ventilated lung.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. A Novel Computed Tomography Score Reveals More about Air Trapping in Asthma.American journal of respiratory and critical care medicine · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. An American Physiological Society cross-journal Call for Papers on "The Physiology of Obesity".American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  12. Reference equations for oscillometry and their differences among populations: a systematic scoping review.European respiratory review : an official journal of the European Respiratory Society · 2022
    Article
  13. Review
  14. Therapeutic ketosis decreases methacholine hyperresponsiveness in mouse models of inherent obese asthma.American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  15. Article
  16. Article
  17. Oscillometry of the respiratory system: a translational opportunity not to be missed.American journal of physiology. Lung cellular and molecular physiology · 2021
    Review
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jason H T BatesDepartment of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont.
Ubong PetersDepartment of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont.ORCID 0000-0002-2491-9519
Nirav DaphtaryDepartment of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont.
Erick S MacLeanDepartment of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont.
Kevin HodgdonDepartment of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont.
David A KaminskyDepartment of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont.
Swati BhatawadekarDepartment of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont.
Anne E DixonDepartment of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont.
University of Vermont · US

Funding

Non-Allergic Late-Onset Asthma of Obesity: Pathophysiology and TherapyR01HL130847 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BATES, JASON HT, DIXON, ANNE E · 2016 to 2019
$2.3M
NHLBI NIH HHS HL-130847NHLBI NIH HHS R01 HL130847
6 · The paper itself

Abstract

The obesity epidemic is causing a rise in asthma incidence due to the appearance of an obesity-specific late-onset nonallergic (LONA) phenotype. We investigated why only a subset of obese participants develop LONA asthma by determining how obesity, both alone and in combination with LONA asthma, affects the volume dependence of respiratory system impedance. We also determined how obesity and asthma affect impedance during and following challenge with the PC

Indexed as

AsthmaBronchial Provocation TestsForced Expiratory VolumeHumansMethacholine ChlorideObesityMethacholine Chlorideairway resistanceairway wall compliancemathematical modelrespiratory system impedance

Identifiers

PMID33119471
PMCPMC7944930
OpenAlexW3095968570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.