ArticleDiabetes/metabolism research and reviews2021
Adult-onset diabetes in Middle Eastern immigrants to Sweden: Novel subgroups and diabetic complications-The All New Diabetes in Scania cohort diabetic complications and ethnicity.
Article in Diabetes/metabolism research and reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Clinical and laboratory characteristics of novel diabetes subgroups: A systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Prediabetes Subgroups, Type 2 Diabetes Risk, and Differential Effects of Preventive Interventions.The Journal of clinical endocrinology and metabolism · 2025 · on this mapTrial
- Validation of the classification for type 2 diabetes into five subgroups: a report from the ORIGIN trial.Diabetologia · 2022Trial
- Enriched Metabolic Phenotyping Refines Phenotypic Resolution of Type 2 Diabetes.Diabetes, obesity & metabolism · 2026Article
- Inequalities in type 2 diabetes incidence in a multiethnic population: a cohort study investigating the impact of ethnicity, migration and mental health comorbidities.Diabetologia · 2026Article
- Prevention of type 2 diabetes in migrant populations from low- and middle-income countries living in high-income countries.Diabetologia · 2025Review
- Causal associations between gut microbiota and type 2 diabetes mellitus subtypes: a mendelian randomization analysis.BMC endocrine disorders · 2025Article
- Risk factors for diabetes in recently arrived migrants in Scania, Sweden compared to the general population.Frontiers in public health · 2025Article
- Association of SMuRFs with cardiovascular risk factors, disease burden, and pharmacological management in Middle Eastern patients with ASCVD and a family history of premature CVD.Frontiers in cardiovascular medicine · 2025Article
- Article
- Undiagnosed type 2 diabetes is common - intensified screening of established risk groups is imperative in Sweden: the SDPP cohort.BMC medicine · 2024Article
- Knowledge about diabetes in Malmö prior to initiation of "Cities Changing Diabetes".Frontiers in public health · 2024Review
- Characteristics of glucolipid metabolism and complications in novel cluster-based diabetes subgroups: a retrospective study.Lipids in health and disease · 2023Article
- The association of copeptin with metabolic risk markers is modified by region of origin.Scientific reports · 2023Article
- A novel diabetes typology: towards precision diabetology from pathogenesis to treatment.Diabetologia · 2022Review
- Phenotypic and genetic classification of diabetes.Diabetologia · 2022Review
- Quantitative myocardial perfusion during stress using CMR is impaired in healthy Middle Eastern immigrants without CV risk factors.Scientific reports · 2022Article
- Insulin secretion and action with increasing age - A comparison between Middle Eastern immigrants and native Swedes.Heliyon · 2022Article
- Postprandial triglyceride levels rather than fat distribution may reflect early signs of disturbed fat metabolism in Iraqi immigrants.Lipids in health and disease · 2022Observational
- Cardiorenal Risk Profiles Among Data-Driven Type 2 Diabetes Sub-Phenotypes: AFrontiers in endocrinology · 2022Article
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Authors and funding
6 authors at 1 institution in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundMiddle Eastern immigrants to Europe represent a high risk population for type 2 diabetes. We compared prevalence of novel subgroups and assessed risk of diabetic macro- and microvascular complications between diabetes patients of Middle Eastern and European origin.
methodsThis study included newly diagnosed diabetes patients born in Sweden (N = 10641) or Iraq (N = 286), previously included in the All New Diabetes in Scania cohort. The study was conducted between January 2008 and August 2016. Patients were followed to April 2017. Incidence rates in diabetic macro- and microvascular complications were assessed using cox-regression adjusting for the confounding effect of age at onset, sex, anthropometrics, glomerular filtration rate (eGFR) and HbA1c.
findingsIn Iraqi immigrants versus native Swedes, severe insulin-deficient diabetes was almost twice as common (27.9 vs. 16.2% p < 0.001) but severe insulin-resistant diabetes was less prevalent. Patients born in Iraq had higher risk of coronary events (hazard ratio [HR] 1.84, 95% CI 1.06-3.12) but considerably lower risk of chronic kidney disease (CKD) than Swedes (HR 0.19; 0.05-0.76). The lower risk in Iraqi immigrants was partially attributed to better eGFR. Genetic risk scores (GRS) showed more genetic variants associated with poor insulin secretion but lower risk of insulin resistance in the Iraqi than native Swedish group.
interpretationPeople with diabetes, born in the Middle East present with a more insulin-deficient phenotype and genotype than native Swedes. They have a higher risk of coronary events but lower risk of CKD. Ethnic differences should be considered in the preventive work towards diabetes and its complications.
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