Evidence map›Paper›PMID 33118127›Full record

ArticleBehavior genetics2021

Etiological Overlap Between Sex Under the Influence and Number of Lifetime Sexual Partners.

Brooke M Huibregtse, Alexander S Hatoum, Robin P Corley, Sally Ann Rhea, John K Hewitt, Michael C Stallings

Open access · greenAbstract read
In one paragraph

Article in Behavior genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Brooke M HuibregtseInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA. brooke.huibregtse@colorado.edu.ORCID http://orcid.org/0000-0003-0977-7249
Alexander S HatoumDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Robin P CorleyInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
Sally Ann RheaInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
John K HewittInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
Michael C StallingsInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
University of Colorado Boulder · USWashington University in St. Louis · US

Funding

Twin StudyP60DA011015 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HEWITT, JOHN K. · 1997 to 2013
$22.5M
Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife2)R01AG046938 · NIA · UNIVERSITY OF COLORADO · PI REYNOLDS, CHANDRA A, WADSWORTH, SALLY J · 2015 to 2024
$18.5M
BIOMEDICAL RESEARCH TRAINING IN DRUG ABUSET32DA007261 · NIDA · WASHINGTON UNIVERSITY · PI ARPANA AGRAWAL, Jose A Moron-Concepcion · 1991 to 2026
$8.8M
Research Training: Mental Health Behavior GeneticsT32MH016880 · NIMH · UNIVERSITY OF COLORADO AT BOULDER · PI Naomi P. Friedman, Matthew Charles Keller · 1985 to 2026
$5.3M
Research Training-Genetics of Substance AbuseT32DA017637 · NIDA · UNIVERSITY OF COLORADO AT BOULDER · PI STITZEL, JERRY A · 2004 to 2023
$5.3M
Genetics and Progression of Early-onset Substance Dependence and HIV RiskR01DA035804 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HOPFER, CHRISTIAN J, STALLINGS, MICHAEL CRAIG · 2014 to 2018
$4.9M
University of Colorado Interdisciplinary Training in Demography and GeneticsT32AG052371 · NIA · UNIVERSITY OF COLORADO · PI BOARDMAN, JASON D · 2017 to 2020
$681k
NIA NIH HHS R01 AG046938NIA NIH HHS T32AG052371NIDA NIH HHS P60 DA011015NIDA NIH HHS R01 DA035804NIDA NIH HHS T32 DA007261NIDA NIH HHS T32 DA017637NIMH NIH HHS T32 MH016880
6 · The paper itself

Abstract

Drug and alcohol use is associated with risky sexual behavior (RSB). It is unclear whether this association is due to correlated liabilities (e.g., third variables influencing both traits), or whether use of drugs and alcohol during sexual decision making increases RSB. This study addresses this question by fitting a series of biometrical models using over 800 twin pairs assessed in early adulthood (m = 25.21 years). Measures included an index of sex under the influence (e.g., frequency that drugs or alcohol affect sexual decision making), number of lifetime sexual partners, and a general measure of substance use. Analyses suggest the covariance among these measures is explained by both genetic and environmental correlated liabilities. The overlap was not specific to sex under the influence, but was shared with a measure of general substance use. Models testing necessary but not sufficient parameters for direction of causation suggest that sex under the influence is unlikely to cause an increase in RSB; more evidence for reverse causation was found.

Indexed as

AdultAlcohol DrinkingBiobehavioral SciencesDecision MakingFemaleHumansMaleRisk-TakingSexual BehaviorSexual PartnersSubstance-Related DisordersTwinsYoung AdultAlcohol useCausal assumptionsRisky sexSubstance useTwins

Identifiers

PMID33118127
PMCPMC8092413
OpenAlexW3097336486

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.