Evidence map›Paper›PMID 33118089›Full record

ArticleFish physiology and biochemistry2021

Distribution and expression of GnRH 1, kiss receptor 2, and estradiol α and ß receptors in the anterior brain of females of Chirostoma humboldtianum.

Beatriz Macedo-Garzón, Rosaura Loredo-Ranjel, Mónica Chávez-Maldonado, J Rafael Jiménez-Flores, Tomás E Villamar-Duque, Rodolfo Cárdenas

Abstract read
PubMed Publisher
In one paragraph

Article in Fish physiology and biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Beatriz Macedo-GarzónLaboratorio de Endocrinología de peces, Unidad de Morfología y Función, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios # 1, Los Reyes Iztacacala, 54090, Tlalnepantla, Edo. de México, México.
Rosaura Loredo-RanjelLaboratorio de Endocrinología de peces, Unidad de Morfología y Función, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios # 1, Los Reyes Iztacacala, 54090, Tlalnepantla, Edo. de México, México.
Mónica Chávez-MaldonadoLaboratorio de Endocrinología de peces, Unidad de Morfología y Función, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios # 1, Los Reyes Iztacacala, 54090, Tlalnepantla, Edo. de México, México.
J Rafael Jiménez-FloresLaboratorio de Inmunología, Unidad de Morfología y Función, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de lo Barrios # 1, Los Reyes Iztacala, 54090, Tlalnepantla, Edo. de México, México.
Tomás E Villamar-DuqueBioterio General, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios # 1, Los Reyes Iztacala, 54090, Tlalnepantla, Edo. de México, México.
Rodolfo CárdenasLaboratorio de Endocrinología de peces, Unidad de Morfología y Función, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios # 1, Los Reyes Iztacacala, 54090, Tlalnepantla, Edo. de México, México. rodolf@unam.mx.ORCID http://orcid.org/0000-0002-8199-5518
Autonomous University of Tlaxcala · MX

Funding

PAPIIT, DGAPA, UNAM. IN217116
6 · The paper itself

Abstract

Reproduction in vertebrates is a complex process regulated by many hormones, and by paracrine factors and their receptors. This study aimed to examine the expression of pjGonadotropin-releasing hormone (GnRH 1), the kisspeptin receptor 2 (kissr2), and estradiol receptors α and β (ER α and ER β) during different stages of the sexual cycle and their distribution within the anterior brain of females of Chirostoma humboldtianum. Among these molecules, the kissr2 showed the maximal variation in expression, while GnRH 1 showed minimal variation of expression, and ERβ and ERα had intermediate variation of expression. The distribution of these molecules in the anterior brain was consistent with their levels of expression; kissr2 was widely distributed throughout the telencephalon and diencephalon, while ER and GnRH 1 showed more restricted distributions. No coexpression of kissr2 and ER in GnRH 1ergic neurons, suggesting that regulation of this GnRH variant is indirectly mediated by kisspeptin and estradiol.

Indexed as

AnimalsBrainEstrogen Receptor alphaEstrogen Receptor betaFemaleFishesFish ProteinsGonadotropin-Releasing HormoneKisspeptinsPituitary GlandEstrogen Receptor alphaEstrogen Receptor betaFish ProteinsGonadotropin-Releasing HormoneKisspeptinsBrainChirostomaEstradiol receptorGnRH 1Kiss receptor

Identifiers

PMID33118089
OpenAlexW3095068665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.