ReviewFrontiers in veterinary science2020
Current Approaches to the Management of Acute Thoracolumbar Disc Extrusion in Dogs.
Review in Frontiers in veterinary science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 64 citations in OpenAlex.
- Degree of Inflammation in Surgically Obtained Intervertebral Disc Extrusions in a Population of 74 Dogs.Veterinary sciences · 2026Article
- Cervical Pain in Non-Chondrodystrophic Dogs: Associations with Clinical Onset, Neurological Group and Disease Category.Animals : an open access journal from MDPI · 2026Article
- Adjunctive Interferential Electrotherapy Provides Transient Postoperative Analgesia After Hemilaminectomy in Dogs.Animals : an open access journal from MDPI · 2026Article
- Unilateral biportal endoscopy (UBE) spine surgery for thoracolumbar intervertebral disc diseases in dogs: An ex vivo cadaveric and in vivo preclinical study.Veterinary surgery : VS · 2026Article
- Teaching common cognitive biases and associated errors in veterinary neurologic diagnosis using clinical vignettes: a narrative review.Frontiers in veterinary science · 2026Review
- Chronic sequelae and owner burdens are common following canine intervertebral disc disease.The Veterinary record · 2025Article
- Recurrence of cervical intervertebral disc extrusion in 55 dogs after surgical decompression with or without prophylactic fenestration.Veterinary surgery : VS · 2025Article
- Combining Metabolomics and Proteomics to Reveal Key Serum Compounds Related to Canine Intervertebral Disc Herniation.Metabolites · 2025Article
- Outcomes of non-limited versus cranial-limited extensive hemilaminectomy and durotomy in dogs with thoracolumbar intervertebral disc extrusion and presumptive progressive myelomalacia.BMC veterinary research · 2025Article
- A Comparative Analysis of Clinical Presentation, Prognosis and Outcomes in Paralytic Dogs with a Compressive and a Contusive Intervertebral Disc Disease.Veterinary sciences · 2025Article
- Tissue damage-induced axon injury-associated responses in sensory neurons: requirements, prevention, and potential role in persistent post-surgical pain.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Accurate Preoperative Localization of Thoracolumbar Disc Extrusion in Dogs: A Prospective Controlled Study.Veterinary sciences · 2024Article
- Physiotherapy in the Recovery of Paraplegic Dogs without Nociception Due to Thoracolumbar Intervertebral Disc Extrusion Treated Surgically.Animals : an open access journal from MDPI · 2024Article
- Lateral fenestration of lumbar intervertebral discs in rabbits: development and characterisation of an in vivo preclinical model with multi-modal endpoint analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Characterization of annulus fibrosus lesions on magnetic resonance imaging in dogs affected by intervertebral disc disease, a descriptive case series.Frontiers in veterinary science · 2024Article
- Recovery of Spinal Walking in Paraplegic Dogs Using Physiotherapy and Supportive Devices to Maintain the Standing Position.Animals : an open access journal from MDPI · 2023Article
- Case report: Neuropathic pain versus undesirable behavior in a Dachshund after hemilaminectomy surgery for an intervertebral disc extrusion.Frontiers in veterinary science · 2023Article
- Clinical, magnetic resonance imaging, surgical features and comparison of surgically treated intervertebral disc extrusion in French bulldogs.Frontiers in veterinary science · 2023Article
- Tridimensional models and radiographic study of dorsal laminectomy and thoracolumbar hemilaminectomy in dogs.Acta cirurgica brasileira · 2023Article
- Approach to Small Animal Neurorehabilitation by Locomotor Training: An Update.Animals : an open access journal from MDPI · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intervertebral disc extrusion (IVDE) is one of the most common neurologic problems encountered in veterinary clinical practice. The purpose of this manuscript is to provide an overview of the literature related to treatment of acute canine thoracolumbar IVDE to help construct a framework for standard care of acute canine thoracolumbar IVDE where sufficient evidence exists and to highlight opportunities for future prospective veterinary clinical research useful to strengthen care recommendations in areas where evidence is low or non-existent. While there exist a number of gaps in the veterinary literature with respect to standards of care for dogs with acute thoracolumbar IVDE, recommendations for standard care can be made in some areas, particularly with respect to surgical decompression where the currently available evidence supports that surgery should be recommended for dogs with nonambulatory paraparesis or worse. While additional information is needed about the influence on timing of decompression on outcome in dogs that are deep pain negative for longer than 48 h duration, there is no evidence to support treatment of the 48 h time point as a cut off beyond which it becomes impossible for dogs to achieve locomotor recovery. Surgical decompression is best accomplished by either hemilaminectomy or mini-hemilaminectomy and fenestration of, at a minimum, the acutely ruptured disc. Adjacent discs easily accessed by way of the same approach should be considered for fenestration given the evidence that this substantially reduces future herniation at fenestrated sites. Currently available neuroprotective strategies such as high does MPSS and PEG are not recommended due to lack of demonstrated treatment effect in randomized controlled trials, although the role of anti-inflammatory steroids as a protective strategy against progressive myelomalacia and the question of whether anti-inflammatory steroids or NSAIDs provide superior medical therapy require further evaluation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.