ArticleFrontiers in cellular and infection microbiology2020
A New Antifungal Agent (4-phenyl-1, 3-thiazol-2-yl) Hydrazine Induces Oxidative Damage in
Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- New Therapeutic Options for Fusariosis: A Patent Review (2008-2023).Journal of fungi (Basel, Switzerland) · 2025Article
- Systematic identification and characterization of five transcription factors mediating the oxidative stress response in Candida albicans.Microbial pathogenesis · 2024Article
- Discovery of novel thiosemicarbazone derivatives with potent and selective anti-Journal of enzyme inhibition and medicinal chemistry · 2023Article
- Antifungal Properties of Hydrazine-Based Compounds againstAntibiotics (Basel, Switzerland) · 2023Article
- Design, Synthesis and Structure-Activity Relationship Studies of Nicotinamide Derivatives as Potent Antifungal Agents by Disrupting Cell Wall.Molecules (Basel, Switzerland) · 2023Article
- Baicalein Acts against Candida albicans by Targeting Eno1 and Inhibiting Glycolysis.Microbiology spectrum · 2022Article
- An interpretable machine learning approach to identify mechanism of action of antibiotics.Scientific reports · 2022Article
- Oxidative stress response pathways in fungi.Cellular and molecular life sciences : CMLS · 2022Review
- Ethanolic extract ofFrontiers in cellular and infection microbiology · 2022Article
- Mining RNA-Seq Data to Depict HowFrontiers in nutrition · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A gradual rise in immunocompromised patients over past years has led to the increasing incidence of invasive fungal infections. Development of effective fungicides can not only provide new means for clinical treatment, but also reduce the occurrence of fungal resistance. We identified a new antifungal agent (4-phenyl-1, 3-thiazol-2-yl), hydrazine (numbered as 31C) which showed high-efficiency, broad-spectrum and specific activities. The minimum inhibitory concentration of 31C against pathogenic fungi was between 0.0625-4 μg/ml
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.