Evidence map›Paper›PMID 33117705›Full record

ArticleFrontiers in oncology2020

Detection of EGFR Mutations in cfDNA and CTCs, and Comparison to Tumor Tissue in Non-Small-Cell-Lung-Cancer (NSCLC) Patients.

Haiyan E Liu, Meghah Vuppalapaty, Charles Wilkerson, Corinne Renier, Michael Chiu, Clementine Lemaire, James Che, Melissa Matsumoto, James Carroll, Steve Crouse and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 52 citations in OpenAlex.

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  15. A prospective phase 2 study of expeditiousTranslational lung cancer research · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Haiyan E LiuVortex Biosciences, Inc., Pleasanton, CA, United States.
Meghah VuppalapatyVortex Biosciences, Inc., Pleasanton, CA, United States.
Charles WilkersonVortex Biosciences, Inc., Pleasanton, CA, United States.
Corinne RenierVortex Biosciences, Inc., Pleasanton, CA, United States.
Michael ChiuVortex Biosciences, Inc., Pleasanton, CA, United States.
Clementine LemaireVortex Biosciences, Inc., Pleasanton, CA, United States.
James CheVortex Biosciences, Inc., Pleasanton, CA, United States.
Melissa MatsumotoDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States.
James CarrollDepartment of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States.
Steve CrouseVortex Biosciences, Inc., Pleasanton, CA, United States.
Violet R HanftDepartment of Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Stefanie S JeffreyDepartment of Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Dino Di CarloDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States.
Edward B GaronDepartment of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States.
Jonathan GoldmanDepartment of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States.
Elodie SollierVortex Biosciences, Inc., Pleasanton, CA, United States.
UCLA Jonsson Comprehensive Cancer CenterStanford University · USUniversity of California, Los Angeles · US

Funding

A model for predicting response to PD-1 inhibitors in NSCLCR01CA208403 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GARON, EDWARD B · 2017 to 2021
$3.2M
NCI NIH HHS R01 CA208403
6 · The paper itself

Abstract

Lung cancer is the leading cause of cancer-related mortality worldwide. Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) therapies, based on the evaluation of

Indexed as

circulating free DNA (cfDNA)circulating tumor biomarkerscirculating tumor cellEGFR mutation analysisepidermal grow factor receptorNon-small cell carcinomatotal liquid biopsyVortex technology

Identifiers

PMID33117705
PMCPMC7578230
OpenAlexW3091799390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.