ArticleFrontiers in oncology2020
Microwave Ablation Versus Nipple Sparing Mastectomy for Breast Cancer ≤5 cm: A Pilot Cohort Study.
Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07263451 (Safety and Feasibility of Irreversible Electroporation for Early-stage Breast Cancer), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Feasibility of Irreversible Electroporation for Early-stage Breast Cancer: a Prospective, Open-Label, Single-Arm, Exploratory Study
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Percutaneous Management of Breast Cancer: a Systematic Review.Current oncology reports · 2022Pooled it
- Interventional Radiology in the Management of Breast Cancer: Current Role and Future Directions.Cardiovascular and interventional radiology · 2026Review
- Ultrasound-guided microwave ablation for breast tumors: current status and future perspectives.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Review
- A Decade Later: An Updated Systematic Review and Meta-analysis of Overall Survival, Disease-Free Survival, Local Recurrence, and Nipple-Areolar Recurrence Following Nipple-Sparing Mastectomy.Annals of surgical oncology · 2026Article
- Transarterial infusion chemotherapy combined with microwave ablation for inoperable triple-negative breast cancer: a case report.Frontiers in oncology · 2026Article
- Comparison of local effects and systemic T-cell responses in patients with breast cancer treated by radiofrequency ablation versus microwave ablation.Cancer cell international · 2025Article
- Clinical effect of ultrasound-guided microwave ablation in the treatment of 60 patients with non-puerperal mastitis.BMC women's health · 2025Article
- Review
- Imaging in Interventional Radiology: Breast Cryoablation.Seminars in interventional radiology · 2025Review
- Ultrasound- guided microwave ablation for symptomatic breast cysts: early outcomes and clinical implications.Frontiers in surgery · 2025Article
- Application of cryoablation in animal models of bladder and muscle-invasive bladder cancer: a narrative review of current status and future perspectives.Quantitative imaging in medicine and surgery · 2024Review
- Microwave Thermal Ablation for Breast Cancer in Africa: A Pioneering Case Report Utilizing TATOpro.Cureus · 2024Article
- Magnetic resonance imaging-guided radiofrequency ablation of breast cancer: a current state of the art review.Diagnostic and interventional radiology (Ankara, Turkey) · 2024Article
- Article
- Emerging Indications for Interventional Oncology: Expert Discussion on New Locoregional Treatments.Cancers · 2023Review
- Heat treatment-induced autophagy promotes breast cancer cell invasion and metastasis via TGF-PeerJ · 2023Article
- Ablative Therapies for Breast Cancer: State of Art.Technology in cancer research & treatmentReview
- Agar-based Phantom for Evaluating Targeting of High-intensity Focused Ultrasound Systems for Breast Ablation.Journal of medical physicsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesCompared with nipple sparing mastectomy (NSM), microwave ablation (MWA) is one relatively new modality indicated for selected breast cancer with nipple sparing and with little of evidence-based medical research for decision-making. The objective of this study was to compare the effect of ultrasound-guided percutaneous MWA and NSM for breast cancer. MATERIALS AND
methodsA retrospective cohort study was conducted in a single institution from 2014 to 2020. Women with invasive ductal carcinoma of the breast ≤ 5cm treated by MWA or NSM were enrolled. The primary end point was tumor progression and secondary end points included survival, cosmetic results, and complications.
results21 patients in the MWA group and 43 in the NSM group were evaluated. The mean tumor size was 2.3 cm (range, 0.3-5.0 cm). Median follow-up was 26.7 months (range, 14.6-62.5 months). The mean age of MWA was 24 years older than that of the NSM group. All the patients achieved technique effectiveness. One local tumor progression and one ipsilateral breast recurrence occurred at 42 and 28 months after MWA, respectively. One ipsilateral breast recurrence and two bone metastasis occurred at 31.2, 34, and 30.5 months after NSM. Two groups had no significant difference in tumor progression (P = 0.16). No participants in both groups developed cancer related death (P > 0.99) and major complications (P > 0.99). However, MWA needed less hospitalization time (P < 0.001) and achieved better cosmetic results (P < 0.001).
conclusionsMWA achieved similar short term effect for breast cancer control and better cosmetic satisfaction compared with NSM in selected patients. MWA provides appropriate option for elderly patients who are unfit for surgery.
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