Evidence map›Paper›PMID 33117626›Full record

Article3 Biotech2020

miR-224 targets

Qi Zheng, Jane J Yu, Chenggang Li, Jiali Li, Jiping Wang, Shuyang Wang

Open access · hybridAbstract read
In one paragraph

Article in 3 Biotech, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. The Advances in Epigenetics for Cancer Radiotherapy.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Article
  8. Article
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  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Qi ZhengDepartment of Pathology, School of Basic Medical Sciences, Fudan University, 131 Dong'an Road, Shanghai, 200032 Shanghai China.
Jane J YuDepartment of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267 USA.
Chenggang LiState Key Laboratory of Medical Chemical Biology and College of Pharmacy, Nankai University, Tianjin, China.
Jiali LiDepartment of Pathology, Huashan Hospital, Fudan University, Shanghai, China.
Jiping WangDivision of Surgical Oncology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA USA.
Shuyang WangDepartment of Pathology, School of Basic Medical Sciences, Fudan University, 131 Dong'an Road, Shanghai, 200032 Shanghai China.ORCID 0000-0003-4284-9216
Shanghai Medical College of Fudan University · CNBrigham and Women's Hospital · USFudan University · CNNankai University · CNUniversity of Cincinnati Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study aims to investigate the impact of miR-224 on cell migration and invasion in colorectal cancer (CRC) as well as its molecular mechanisms. The results showed that miR-224 was significantly upregulated in CRC compared to normal tissues via the TCGA database. Overexpression of miR-224 promoted CRC cell migration and invasion, while inhibition of miR-224 demonstrated the opposite result via transwell assays. In addition, we found that

Indexed as

Beta-TrCPBTRCColorectal cancerCRCMicroRNAmiR-224

Identifiers

PMID33117626
PMCPMC7585582
OpenAlexW3094045361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.