Trial reportFrontiers in endocrinology2020
Higher Muscle Mass Implies Increased Free-Thyroxine to Free-Triiodothyronine Ratio in Subjects With Overweight and Obesity.
Trial report in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04327375 (Effect of Body Composition on Thyroid Hormone Levels Among Overweight and Obese Subjects), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Body Composition on Thyroid Hormone Levels Among Overweight and Obese Subjects
Who cites it
16 citing papers in PubMed, 21 citations in OpenAlex.
- Peripheral Thyroid Hormone Sensitivity Mediates the Association Between Body Composition and Diabetes in Euthyroid Adults.Journal of cachexia, sarcopenia and muscle · 2025Article
- The FTJournal of clinical medicine · 2025Article
- Association Between Euthyroidism and Muscular Parameters in Adults with an Excess of Fat Mass: A Preliminary Study.Healthcare (Basel, Switzerland) · 2025Article
- Association between free T3 and sarcopenia in euthyroid older patients with Hashimoto's thyroiditis.Frontiers in endocrinology · 2025Article
- Chronic thyrotoxic myopathy development is associated with thyroid hormone sensitivity index, predicted by lower-limb fatigue and the squat-up test.Scientific reports · 2024Article
- The association between serum soluble α-Klotho and thyroid profile among adults from NHANES 2007-2012.BMC endocrine disorders · 2024Article
- Cross-sectional associations between healthy eating index and thyroid function in U.S. male Adults, NHANES 2007-2012.Food science & nutrition · 2023Article
- Higher Sensitivity to Thyroid Hormones May Be Linked to Maintaining the Healthy Metabolic Condition in People with Obesity: New Insight from NHANES.Obesity facts · 2023Article
- Circulating free T3 associates longitudinally with cardio-metabolic risk factors in euthyroid children with higher TSH.Frontiers in endocrinology · 2023Article
- Association between the Systemic Immune-Inflammation Index and Thyroid Function in U.S. Adults.Mediators of inflammation · 2023Article
- The serum free triiodothyronine to free thyroxine ratio as a potential prognostic biomarker of chronic kidney disease in patients with glomerular crescents: A retrospective study.Frontiers in endocrinology · 2022Article
- Muscle Fat Content Is Strongly Associated With Hyperuricemia: A Cross-Sectional Study in Chinese Adults.Frontiers in endocrinology · 2022Article
- Association between thyroid hormones and skeletal muscle and bone in euthyroid type 2 diabetes patients.Therapeutic advances in chronic disease · 2022Article
- Central Obesity Is Associated with Variations in TSH and ACTH Levels among Euthyroid Obese Individuals.International journal of endocrinology · 2022Article
- Association of Reduced Free T3 to Free T4 Ratio with Lower Serum Creatinine in Japanese Hemodialysis Patients.Nutrients · 2021Article
- The Association between the Dietary Inflammatory Index and Thyroid Function in U.S. Adult Males.Nutrients · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thyroid hormones control both metabolic pathways and body composition, whereas little knowledge is available about the possible influence of skeletal muscle mass (MM) on thyroid hormone metabolism and circulating levels. This was a cross-sectional study conducted at the Population Health Unit of the National Institute of Gastroenterology IRCCS "S. de Bellis" (Italy) and investigating the extent to which skeletal MM affects thyroid function in obesity. Two hundred twenty-seven consecutive healthy volunteers (155 women and 72 men) with overweight and obesity (BMI ≥ 25 kg/m Clinical Trial Registration: ClinicalTrials.gov, identifier NCT04327375.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.