Evidence map›Paper›PMID 33117275›Full record

ReviewFrontiers in endocrinology2020

An Update in Qualitative Imaging of Bone Using Ultrashort Echo Time Magnetic Resonance.

Saeed Jerban, Douglas G Chang, Yajun Ma, Hyungseok Jang, Eric Y Chang, Jiang Du

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Development and assessment of anImaging science in dentistry · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. QuantitativeJournal of magnetic resonance imaging : JMRI · 2024
    Article
  9. Ultrashort echo time MRI detects significantly lower collagen but higher pore water in the tibial cortex of female patients with osteopenia and osteoporosis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Article
  10. QuantitativeBone · 2024
    Article
  11. Article
  12. Bone Biomarkers Based on Magnetic Resonance Imaging.Seminars in musculoskeletal radiology · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. MR Imaging of the Pelvic Bones: The Current and Cutting-Edge Techniques.Journal of the Belgian Society of Radiology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Saeed JerbanDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
Douglas G ChangDepartments of Orthopaedic Surgery, University of California, San Diego, San Diego, CA, United States.
Yajun MaDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
Hyungseok JangDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
Eric Y ChangDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
Jiang DuDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
University of California, San Diego · US

Funding

Ultrashort Echo Time (UTE) Magnetic Resonance Imaging of BoneR01AR068987 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2015 to 2024
$4.9M
Quantitative UTE MR Imaging: Sensitive Biomarkers for OsteoarthritisR01AR062581 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2013 to 2022
$4.1M
Three-dimensional Ultrashort Echo Time Magnetic Resonance Imaging of EnthesesR01AR075825 · NIAMS · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI CHANG, ERIC Y · 2019 to 2023
$1.8M
Three-Dimensional UTE Magnetic Resonance Imaging of the Osteochondral JunctionR21AR075851 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MA, YAJUN · 2020 to 2021
$376k
Ultrashort Echo Time Magnetic Resonance Imaging of Bone Stress InjuriesR21AR073496 · NIAMS · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI CHANG, ERIC Y · 2018 to 2019
$343k
Non-invasive Morphologic and Biochemical Assessment of Tendon with Novel UTE-MRIIK2CX000749 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2012 to 2015
–
Quantitative Measurement of Joint pH with Magnetic Resonance ImagingI01RX002604 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2018 to 2022
–
CSRD VA IK2 CX000749NIAMS NIH HHS R01 AR062581NIAMS NIH HHS R01 AR068987NIAMS NIH HHS R01 AR075825NIAMS NIH HHS R21 AR073496NIAMS NIH HHS R21 AR075851
6 · The paper itself

Abstract

Bone is comprised of mineral, collagenous organic matrix, and water. X-ray-based techniques are the standard approach for bone evaluation in clinics, but they are unable to detect the organic matrix and water components in bone. Magnetic resonance imaging (MRI) is being used increasingly for bone evaluation. While MRI can non-invasively assess the proton pools in soft tissues, cortical bone typically appears as a signal void with clinical MR techniques because of its short T2*. New MRI techniques have been recently developed to image bone while avoiding the ionizing radiation present in x-ray-based methods. Qualitative bone imaging can be achieved using ultrashort echo time (UTE), single inversion recovery UTE (IR-UTE), dual-inversion recovery UTE (Dual-IR-UTE), double-inversion recovery UTE (Double-IR-UTE), and zero echo time (ZTE) sequences. The contrast mechanisms as well as the advantages and disadvantages of each technique are discussed.

Indexed as

Bone and BonesCortical BoneHumansMagnetic Resonance Imagingcortical boneMRIsingle inversion recovery UTEtrabecular boneUTE–ultra-short TEzero echo time MRI

Identifiers

PMID33117275
PMCPMC7551122
OpenAlexW3089995439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.