Evidence map›Paper›PMID 33117257›Full record

ArticleFrontiers in neurology2020

Serum Protein Biomarker Findings Reflective of Oxidative Stress and Vascular Abnormalities in Male, but Not Female, Collision Sport Athletes.

Brendan P Major, Stuart J McDonald, William T O'Brien, Georgia F Symons, Meaghan Clough, Daniel Costello, Mujun Sun, Rhys D Brady, Jesse Mccullough, Roxanne Aniceto and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Treatment with the vascular endothelial growth factor-A antibody, bevacizumab, has sex-specific effects in a rat model of mild traumatic brain injury.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
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  11. Concussion and long-term cognitive function among rugby players-The BRAIN Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Brendan P MajorDepartment of Neuroscience, Monash University, Melbourne, VIC, Australia.
Stuart J McDonaldDepartment of Neuroscience, Monash University, Melbourne, VIC, Australia.
William T O'BrienDepartment of Neuroscience, Monash University, Melbourne, VIC, Australia.
Georgia F SymonsDepartment of Neuroscience, Monash University, Melbourne, VIC, Australia.
Meaghan CloughDepartment of Neuroscience, Monash University, Melbourne, VIC, Australia.
Daniel CostelloDepartment of Medicine, The University of Melbourne, Parkville, VIC, Australia.
Mujun SunDepartment of Neuroscience, Monash University, Melbourne, VIC, Australia.
Rhys D BradyDepartment of Neuroscience, Monash University, Melbourne, VIC, Australia.
Jesse McculloughDepartment of Anatomy, Physiology, and Genetics, Uniformed Services University, Bethesda, MD, United States.
Roxanne AnicetoDepartment of Anatomy, Physiology, and Genetics, Uniformed Services University, Bethesda, MD, United States.
I-Hsuan LinDepartment of Anatomy, Physiology, and Genetics, Uniformed Services University, Bethesda, MD, United States.
Meng LawDepartment of Neuroscience, Monash University, Melbourne, VIC, Australia.
Richelle MychasiukDepartment of Neuroscience, Monash University, Melbourne, VIC, Australia.
Terence J O'BrienDepartment of Neuroscience, Monash University, Melbourne, VIC, Australia.
Denes V AgostonDepartment of Anatomy, Physiology, and Genetics, Uniformed Services University, Bethesda, MD, United States.
Sandy R ShultzDepartment of Neuroscience, Monash University, Melbourne, VIC, Australia.
Monash University · AUUniformed Services University of the Health Sciences · USUniversity of Melbourne · AULa Trobe University · AUUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have indicated that concussive and sub-concussive brain injuries that are frequent during collision sports may lead to long-term neurological abnormalities, however there is a knowledge gap on how biological sex modifies outcomes. Blood-based biomarkers can help to identify the molecular pathology induced by brain injuries and to better understand how biological sex affects the molecular changes. We therefore analyzed serum protein biomarkers in male (

Indexed as

4-HNEcerebrovascularconcussionmild TBIsub-concussionvascular injuryVEGF–vascular endothelial growth factor

Identifiers

PMID33117257
PMCPMC7561422
OpenAlexW3091540001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.