Evidence map›Paper›PMID 33117256›Full record

ArticleFrontiers in neurology2020

Intrinsic Auricular Muscle Zone Stimulation Improves Walking Parameters of Parkinson's Patients Faster Than Levodopa in the Motion Capture Analysis: A Pilot Study.

Yusuf O Cakmak, Burak Ozsoy, Sibel Ertan, Ozgur O Cakmak, Gunes Kiziltan, Hale Yapici-Eser, Ecem Ozyaprak, Selim Olcer, Hakan Urey, Yasemin Gursoy-Ozdemir

Abstract read
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yusuf O CakmakCakmak Lab, Department of Anatomy, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Burak OzsoyCakmak Lab, Department of Anatomy, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Sibel ErtanDepartment of Neurology, School of Medicine, Koc University Research Centre for Translational Medicine (KUTTAM), Koç University, Istanbul, Turkey.
Ozgur O CakmakDepartment of Neurology, School of Medicine, Koc University Research Centre for Translational Medicine (KUTTAM), Koç University, Istanbul, Turkey.
Gunes KiziltanDepartment of Neurology, Cerrahpaşa School of Medicine, Istanbul University, Istanbul, Turkey.
Hale Yapici-EserDepartment of Psychiatry, School of Medicine, Koç University, Istanbul, Turkey.
Ecem OzyaprakDepartment of Neurology, School of Medicine, Koc University Research Centre for Translational Medicine (KUTTAM), Koç University, Istanbul, Turkey.
Selim OlcerDepartment of Electrical Engineering, College of Engineering, Koç University, Istanbul, Turkey.
Hakan UreyDepartment of Electrical Engineering, College of Engineering, Koç University, Istanbul, Turkey.
Yasemin Gursoy-OzdemirDepartment of Neurology, School of Medicine, Koc University Research Centre for Translational Medicine (KUTTAM), Koç University, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been demonstrated that intrinsic auricular muscles zone stimulation (IAMZS) can improve the motor symptoms of Parkinson's disease (PD) patients who are examined with the Unified Parkinson's Disease Rating Scale (UPDRS) motor scores. In the present pilot study, using motion capture technology, we aimed to investigate the efficacy of IAMZS compared to medication alone or in combination with medication. Ten PD patients (mean age: 54.8 ± 10.1 years) were enrolled. Each participant participated in three different sessions: sole medication, sole stimulation-20 min of IAMZS, and combined IAMZS (20 min) and medication. Each session was performed on different days but at the same time to be aligned with patients' drug intake. Motion capture recording sessions took place at baseline, 20, 40, and 60 min. Statistical analysis was conducted using one-way repeated measures ANOVA. Bonferroni correction was implemented for pairwise comparisons. The sole medication was ineffective to improve gait-related parameters of stride length, stride velocity, stance, swing, and turning speed. In the sole-stimulation group, pace-related gait parameters were significantly increased at 20 and 40 min. These improvements were observed in stride length at 20 (

Indexed as

auricular muscleelectrostimulationmotion capturemotor symptomsParkinson's diseasewalking

Identifiers

PMID33117256
PMCPMC7575762

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.