Trial reportNature and science of sleep2020
Effects of Patient-Directed Interactive Music Therapy on Sleep Quality in Postoperative Elderly Patients: A Randomized-Controlled Trial.
Trial report in Nature and science of sleep, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03156205 (Effects of Patient-Directed Interactive Music Therapy on Sleep, Delirium and Melatonin Levels is Critically Ill Elderly Patients), which is not on this map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Patient-Directed Interactive Music Therapy on Sleep, Delirium and Melatonin Levels is Critically Ill Elderly Patients
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Effects of stellate ganglion block on postoperative sleep disturbance: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2026Pooled it
- Effects of non-pharmacological interventions on sleep in patients with critical illness: a systematic review and network meta-analysis.Scientific reports · 2026Pooled it
- Effect of music therapy on sleep quality in elderly: A systematic review and meta-analysis.PloS one · 2025Pooled it
- The role of arts therapies in mitigating Sleep Initiation and Maintenance Disorders: a systematic review.Frontiers in psychiatry · 2024Pooled it
- The Effect of Music and Eye Masks on Sleep Quality and Delirium in Abdominal Surgery Intensive Care Patients: Randomized Controlled Trial.Nursing in critical care · 2025Trial
- Effects of Live Music on the Perception of Noise in the SICU/PICU: A Patient, Caregiver, and Medical Staff Environmental Study.International journal of environmental research and public health · 2023Trial
- [Ultrasound-guided stellate ganglion block improves sleep quality in elderly patients early after thoracoscopic surgery for lung cancer: a randomized controlled study].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022Trial
- Effectiveness of Non-Pharmacological Interventions for the Prevention of Postoperative Delirium in Critically Ill Adult Patients: A Systematic Review and Meta-Analysis.Nursing reports (Pavia, Italy) · 2026Review
- The Impact of Recorded Music on Postoperative Delirium in Older Adults After Hip Fracture Surgery (IPOD): A Quasi-Experimental Study.Journal of the American Geriatrics Society · 2026Article
- Clinical Nursing Management of Adult Patients with Delirium in a Hospital Setting-A Systematic Review.Journal of clinical medicine · 2025Review
- Effects of Chinese traditional five-element music intervention on postoperative delirium and sleep quality in elderly patients after non-cardiac surgery: a randomized controlled trial.Perioperative medicine (London, England) · 2024Article
- Meta-narrative review: the impact of music therapy on sleep and future research directions.Frontiers in neurology · 2024Review
- Sleep and critical illness: a review.Frontiers in medicine · 2023Review
- Music Interventions and Delirium in Adults: A Systematic Literature Review and Meta-Analysis.Brain sciences · 2022Review
- Effects of Traditional Chinese Medicine Anticancer Decoction Combined with Basic Chemotherapy and Nursing Intervention on Oral Cancer Patients after Surgery and Its Effect on Tumor Markers and Immune Function.BioMed research international · 2022Article
- The effects of a team-based planned care program on the quality of sleep in cardiac surgery patients hospitalized in the intensive care unit: A two-group controlled clinical trial.Journal of education and health promotion · 2022Article
- Updated Review of the Acoustic Modulation of Sleep: Current Perspectives and Emerging Concepts.Nature and science of sleep · 2021Review
- Perioperative Sleep Disorder: A Review.Frontiers in medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to investigate the effects of patient-directed interactive music on saliva melatonin levels and sleep quality among postoperative elderly patients in the intensive care unit (ICU). PATIENTS AND
methodsA total of 133 elderly patients were randomized into three groups: interactive music therapy (IMT), passive listening (PL), and the control group. The control group (n = 45) received routine medical care, while IMT and PL groups received music therapy on ICU day 1. The IMT group received up to 20 mins of interactive music sessions, including relaxation techniques. The PL group received only pre-selected relaxing music-listening for 30 mins. Saliva melatonin and cortisol levels were measured three times at 11 p.m. (preoperative, operation day, and postoperative day [POD] 1). The Richards-Campbell Sleep Questionnaire (RCSQ) and Quality of Recovery-40 questionnaire (QoR40) were administered on the preoperative day, as well as PODs 1 and 2.
resultsThe RCSQ showed a significant improvement in the IMT group compared to the control group on POD2 (71.50 vs 56.89, p=0.012), but the QoR40 did not show any difference between groups. The quality control of the saliva sample was not available due to the immediate postoperative patient's condition, resulting in a higher dropout rate. Saliva melatonin levels on POD 1 were elevated in the IMT group compared to the control group (1.45 vs 0.04, p=0.0068). The cortisol level did not show a significant difference between groups.
conclusionSingle IMT intervention improved subjectively assessed short-term sleep quality in postoperative elderly patients. It is difficult to conclude whether music therapy intervention affects the level of melatonin and cortisol.
trial registrationThe study was registered at ClinicalTrials.Gov (number NCT03156205).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.