ReviewOpen access emergency medicine : OAEM2020
Prescribing Buprenorphine for Opioid Use Disorders in the ED: A Review of Best Practices, Barriers, and Future Directions.
Review in Open access emergency medicine : OAEM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Follow-up after ED visits for opioid use disorder: Do they reduce future overdoses?Journal of substance abuse treatment · 2022Pooled it
- A randomized clinical trial of strengths-based case management to link emergency department patients to opioid use disorder treatment.Journal of substance abuse treatment · 2022Trial
- Implementation of an opioid use disorder (OUD) machine-learning phenotype in real-time for the ADAPT clinical trial.PLOS digital health · 2026Article
- A Qualitative Assessment of an Electronic Health Record-Embedded Intervention to Increase In-Hospital Opioid Use Disorder Treatment Initiation.Journal of general internal medicine · 2026Article
- Implementation of an Opioid Use Disorder (OUD) Machine-Learning Phenotype in Real-Time for the ADAPT Project.medRxiv : the preprint server for health sciences · 2025Article
- "Bupe by the book": A study protocol for a pilot randomized controlled trial of library-facilitated telehealth to increase buprenorphine treatment among individuals experiencing homelessness.Addiction science & clinical practice · 2025Article
- Induction of Medication for Opioid Use Disorder in Primary Care.Journal of the American Board of Family Medicine : JABFM · 2025Article
- Interventions to improve access to opioid agonist therapy in acute hospitals: A scoping review.PLOS mental health · 2025Article
- Barriers and facilitators to prescribing buprenorphine for treating opioid use disorder among emergency department and other practice setting physicians.AIMS public health · 2025Article
- Facilitators of and barriers to buprenorphine initiation in the emergency department: a scoping review.Lancet regional health. Americas · 2024Article
- Opioid-specific harm reduction in the emergency department: how staff provide harm reduction and contextual factors that impact their capacity to engage in harm reduction practice.Harm reduction journal · 2024Article
- Overview of best practices for buprenorphine initiation in the emergency department.International journal of emergency medicine · 2024Article
- Strategies to support substance use disorder care transitions from acute-care to community-based settings: a scoping review and typology.Addiction science & clinical practice · 2023Article
- Article
- Physician-Perceived Barriers to Treating Opioid Use Disorder in the Emergency Department.Cureus · 2021Article
- Article
- Thematic Analysis of Reddit Content About Buprenorphine-naloxone Using Manual Annotation and Natural Language Processing Techniques.Journal of addiction medicineArticle
- Barriers to Engagement in Opioid Use Disorder Treatment After Buprenorphine Induction.Journal of addiction medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ED-initiated addiction treatment holds promise for enhancing access to treatment for those with opioid use disorder (OUD). We present a literature review summarizing the evidence for buprenorphine induction in the ED including best practices for dosing, follow-up care, and reducing implementation barriers. A literature search of Pubmed, PsychInfo, and Embase identified articles studying OUD treatment in the ED published after 1980. Twenty-five studies were identified including eleven scientific abstracts. Multiple studies suggest that buprenorphine induction improves engagement in substance treatment up to 30 days after ED treatment. Many different induction protocols were presented, but no particular approach was best supported as criteria for induction and initial dosing vary widely. Similarly, transition of care models focused on either a "hub and spoke" model or "warm hand-offs" model, but no studies compared these approaches. Common barriers to implementing induction programs were provider inexperience, discomfort with addiction treatment, and limited time during the ED visit. No studies described the number of EDs offering induction. While ED buprenorphine induction is safe and enhances adherence to addiction treatment, uncertainty persists in how to best identify patients needing treatment, how to initiate buprenorphine, and how to enhance follow-up after ED-initiated treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.