ArticleCancer management and research2020
Prognostic Nomogram That Predicts Overall Survival of Patients with Distal Cholangiocarcinoma After Pancreatoduodenectomy.
Article in Cancer management and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Proposing preoperative neutrophil percentage-to-albumin ratio as an effective prognostic factor for postoperative prognosis of distal cholangiocarcinoma: a retrospective cohort study.Frontiers in medicine · 2025Article
- Comparing the predictive performance of different lymph node staging systems for postoperative overall survival in patients with ampullary carcinoma.Frontiers in surgery · 2023Article
- A New Prognostic Model Covering All Stages of Intrahepatic Cholangiocarcinoma.Journal of clinical and translational hepatology · 2022Article
- A Nomogram Based on the Log Odds of Positive Lymph Nodes Predicts the Prognosis of Patients With Distal Cholangiocarcinoma After Surgery.Frontiers in surgery · 2021Article
- Comparison of Four Lymph Node Stage Methods for Predicting the Prognosis of Distal Cholangiocarcinoma Patients After Surgery.Frontiers in oncology · 2021Article
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Authors and funding
12 authors.
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Abstract
purposeWe aimed to develop a nomogram for predicting the prognosis of patients with distal cholangiocarcinoma (DCC) and to compare its performance with that of the American Joint Committee on Cancer (AJCC) TNM system. PATIENTS AND
methodsTo develop a nomogram, we collected the clinical data of 147 patients diagnosed with DCC who underwent pancreatoduodenectomy. Predictive accuracy and discriminative ability were determined using a concordance index and a calibration curve. Predictive performance was compared with that of a current staging systems for DCC.
resultsMultivariate analysis revealed that jaundice, alcohol consumption, high fibrinogen, poorly differentiated tumor cells, positive lymph nodes, and positive margins were significantly associated with overall survival. These variables were incorporated into the nomogram. The concordance index of the nomogram for predicting overall survival was 0.737 (P<0.001), which is significantly higher than the concordance index values (concordance index = 0.586) acquired using the AJCC TNM system (eighth edition). The calibration curve agreed well with predicted prediction and observed overall survival.
conclusionWe developed a nomogram for predicting the prognoses of patients with distal cholangiocarcinoma, which had superior practical clinical value compared with that of the AJCC TNM system.
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