Evidence map›Paper›PMID 33116863›Full record

ArticleCancer management and research2020

Construction and Characterization of KRAS Immune Lipid Magnetic Balls for Colorectal Cancer Circulating Tumor Cells.

Chengbao Feng, Jingjing Wang, Xue Yang, Xuefang Zang, Haikun Zhou, Erying Zhang, Haifei Li, Bo Liu, Shumin Chen, Ying Wang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Chengbao FengDepartment of Medical Oncology, No. 2 Hospital of Baoding, Baoding City, People's Republic of China.ORCID 0000-0002-6528-6439
Jingjing WangDepartment of Medical Oncology, No. 2 Hospital of Baoding, Baoding City, People's Republic of China.
Xue YangBaoding Children's Hospital, Baoding City, People's Republic of China.
Xuefang ZangDepartment of Medical Oncology, No. 2 Hospital of Baoding, Baoding City, People's Republic of China.
Haikun ZhouDepartment of Medical Oncology, No. 2 Hospital of Baoding, Baoding City, People's Republic of China.ORCID 0000-0002-7819-7507
Erying ZhangDepartment of Medical Oncology, No. 2 Hospital of Baoding, Baoding City, People's Republic of China.ORCID 0000-0003-1964-1759
Haifei LiDepartment of Medical Oncology, No. 2 Hospital of Baoding, Baoding City, People's Republic of China.
Bo LiuDepartment of Medical Oncology, No. 2 Hospital of Baoding, Baoding City, People's Republic of China.
Shumin ChenDepartment of Medical Oncology, No. 2 Hospital of Baoding, Baoding City, People's Republic of China.
Ying WangDepartment of Medical Oncology, No. 2 Hospital of Baoding, Baoding City, People's Republic of China.
Peng WangDepartment of Medical Oncology, No. 2 Hospital of Baoding, Baoding City, People's Republic of China.
Lixue GaoDepartment of Medical Oncology, No. 2 Hospital of Baoding, Baoding City, People's Republic of China.ORCID 0000-0002-1851-8444
Jinyan LiuDepartment of Medical Oncology, No. 2 Hospital of Baoding, Baoding City, People's Republic of China.ORCID 0000-0002-6810-9657
Baoding People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this study was to prepare and characterize a lipid magnetic ball modified with KRAS antibodies on the surface and to isolate circulating tumor cells of colorectal cancer with

methodsThe microemulsion method was used to form lipid bilayers to encapsulate Fe3O4 nanoparticles with superparamagnetism to form lipid magnetic balls, and

resultsCompared with traditional EpCAM antibody-modified lipid magnetic balls, it can effectively improve the capture ability of colorectal cancer circulating tumor cells with

conclusionOur results showed that

Indexed as

circulating tumor cellscolorectal cancerKRAS mutationlipid magnetic balls

Identifiers

PMID33116863
PMCPMC7568589
OpenAlexW3092620020

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.