ArticleCancer management and research2020
Preoperative Inversed Albumin-to-Globulin Ratio Predicts Worse Oncologic Prognosis Following Curative Hepatectomy for Hepatocellular Carcinoma.
Article in Cancer management and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Radiomics analysis of contrast-enhanced CT for staging liver fibrosis: an update for image biomarker.Hepatology international · 2022Trial
- Linking systemic inflammation to periodontal disease: insights from blood-derived biomarkers in NHANES.Odontology · 2026Article
- Surgery-centered integrated strategies for personalized hepatocellular carcinoma care.Cancer biology & medicine · 2026Review
- Achieving textbook outcome in liver resection for hepatocellular carcinoma: malnutrition's pivotal role.Langenbeck's archives of surgery · 2025Article
- A study investigating how the albumin-globulin ratio relates to depression risk within U.S. adults: a cross-sectional analysis.Frontiers in nutrition · 2024Article
- Non-linear relationship of serum albumin-to-globulin ratio and cognitive function in American older people: a cross-sectional national health and nutrition examination survey 2011-2014 (NHANES) study.Frontiers in public health · 2024Article
- Prognostic significance of globulin/low-density lipoprotein ratio in patients with hepatocellular carcinoma after local ablative therapy: a retrospective cohort study.Translational cancer research · 2023Article
- Preoperative prediction of macrotrabecular-massive hepatocellular carcinoma based on B-Mode US and CEUS.European radiology · 2023Article
- Inversed albumin-to-globulin ratio and underlying liver disease severity as a prognostic factor for survival in hepatocellular carcinoma patients undergoing transarterial chemoembolization.Diagnostic and interventional radiology (Ankara, Turkey) · 2023Article
- Review
- The value of 7 peripheral blood serum ratios in diagnosis and prediction of disease activity of patients within inflammatory bowel disease individuals.Frontiers in medicine · 2023Article
- Serological Biomarkers and Indices for the Current Activity and Prognosis of ANCA-Associated Vasculitis: Experience in a Single Centre in Korea.Yonsei medical journal · 2021Review
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Authors and funding
11 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA normal albumin-to-globulin ratio (NAGR) in serum is greater than 1. Inversed albumin-to-globulin ratio (IAGR < 1) indicates poor synthetic liver function or malnutrition. The aim of this study is to evaluate whether preoperative IAGR was associated with worse oncologic survival after hepatectomy for hepatocellular carcinoma (HCC). PATIENTS AND
methodsPatients who underwent curative hepatectomy for HCC between 2009 and 2016 in four centers were divided into the IAGR and NAGR groups based on their preoperative levels, and their clinical characteristics and long-term survival outcomes were compared. Univariable and multivariable Cox regression analyses were performed to identify risk factors of overall survival (OS) and recurrence-free survival (RFS).
resultsOf 693 enrolled patients, 136 (19.6%) were in the IAGR group. Their 5-year OS and RFS rates were 31.6% and 21.3%, respectively, which were significantly worse than the NAGR group (43.4% and 28.7%, both
conclusionPreoperative IAGR was useful in predicting worse OS and RFS in patients who underwent curative hepatectomy for HCC.
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