Evidence map›Paper›PMID 33116795›Full record

Trial reportJournal of pain research2020

Nucleotides Cytidine and Uridine Associated with Vitamin B12 vs B-Complex Vitamins in the Treatment of Low Back Pain: The NUBES Study.

Marco Antonio Naslausky Mibielli, Carlos Pereira Nunes, Henrique Goldberg, Luiz Buchman, Lisa Oliveira, Spyros G E Mezitis, Fernanda Wajnzstajn, Renato Kaufman, Rafael Nigri, Natasha Cytrynbaum and 8 more

Open access · goldAbstract readCase ReportsClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of pain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 2 countries.

Marco Antonio Naslausky MibielliUNIFESO Medical School, Teresópolis, Brazil.ORCID 0000-0001-7761-8499
Carlos Pereira NunesUNIFESO Medical School, Teresópolis, Brazil.ORCID 0000-0002-8761-312X
Henrique GoldbergInstituto De Pós-Graduação Médica Carlos Chagas (ICC), Rio De Janeiro, Brazil.ORCID 0000-0003-0458-8414
Luiz BuchmanUERJ Medical School, Rio De Janeiro, Brazil.
Lisa OliveiraFederal University of Rio De Janeiro (UFRJ), Rio De Janeiro, Brazil.ORCID 0000-0003-4186-377X
Spyros G E MezitisNew York-Presbyterian Hospital/Weill-Cornell Medical Center, New York, NY, USA.
Fernanda WajnzstajnNeurology Department, UConn Health, Farmington, CT, USA.
Renato KaufmanInstituto De Pós-Graduação Médica Carlos Chagas (ICC), Rio De Janeiro, Brazil.
Rafael NigriDepartment of Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.ORCID 0000-0001-8866-5661
Natasha CytrynbaumInstituto De Pós-Graduação Médica Carlos Chagas (ICC), Rio De Janeiro, Brazil.ORCID 0000-0001-7671-1026
Karin Soares CunhaPathology Department, Universidade Federal Fluminense (UFF) Medical School, Niterói, Brazil.
Alessandra SantosFederal University of Rio De Janeiro (UFRJ), Rio De Janeiro, Brazil.
Stephanie Wrobel GoldbergTufts Medical Center, Boston, MA, USA.
Natália Carvalho PlatenikUNIFESO Medical School, Teresópolis, Brazil.
Helio RzetelnaSanta Casa Da Misericórdia Do Rio De Janeiro, Rio De Janeiro, Brazil.
Daniel Bertoluci FuturoUNIFESO Medical School, Teresópolis, Brazil.ORCID 0000-0001-9298-9247
Adenilson de Souza Da FonsecaUNIFESO Medical School, Teresópolis, Brazil.
Mauro GellerUNIFESO Medical School, Teresópolis, Brazil.ORCID 0000-0002-5108-5054
Centro Universitário Serra dos Órgãos · BRFundação Carlos Chagas · BRUniversidade Federal do Rio de Janeiro · BRUniversidade do Estado do Rio de Janeiro · BRNewYork–Presbyterian Hospital · USRutgers, The State University of New Jersey · USSanta Casa de Misericórdia de Passos · BRTufts Medical Center · USUConn Health · USUniversidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe report the results of low back pain treatment using a combination of nucleotides, uridine (UTP), cytidine (CMP) and vitamin B PATIENTS AND

methodsRandomized, double-blind, controlled trial, of a 60-day oral treatment: Group A (n=317) receiving nucleotides+B

resultsSeventy-five (24%) and 105 (33%) subjects (

conclusionTreatment with nucleotides+B

Indexed as

cytidinelow back painuridinevitamin B1vitamin B12vitamin B6

Identifiers

PMID33116795
PMCPMC7568635
OpenAlexW3091925570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.