Evidence map›Paper›PMID 33116736›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2020

The Relationship Between Vitamin D Deficiency and Glycated Hemoglobin Levels in Patients with Type 2 Diabetes Mellitus.

Hang Zhao, Yunfeng Zhen, Zijing Wang, Licui Qi, Yong Li, Luping Ren, Shuchun Chen

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. A Retrospective Analysis of the Relationship Between 25-OH-Vitamin D and Diabetic Foot Ulcer.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Article
  10. The Relationship Between Triglyceride Glucose Index and Vitamin D in Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Article
  11. Article
  12. The Relationship Between Hemoglobin Glycation Variation Index and Vitamin D in Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hang ZhaoEndocrinology Department, Hebei General Hospital, Shijiazhuang, Hebei 050051, People's Republic of China.ORCID 0000-0002-9531-7574
Yunfeng ZhenEndocrinology Department, Hebei General Hospital, Shijiazhuang, Hebei 050051, People's Republic of China.
Zijing WangEndocrinology Department, Hebei General Hospital, Shijiazhuang, Hebei 050051, People's Republic of China.
Licui QiGraduate School of Hebei North University, Zhangjiakou, Hebei 07500, People's Republic of China.
Yong LiGraduate School of North China University of Science and Technology, Caofeidian New Town, Tangshan, Hebei 063210, People's Republic of China.
Luping Ren *Endocrinology Department, Hebei General Hospital, Shijiazhuang, Hebei 050051, People's Republic of China.
Shuchun Chen *Endocrinology Department, Hebei General Hospital, Shijiazhuang, Hebei 050051, People's Republic of China.
Hebei General Hospital · CNHebei North University · CNNorth China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aims of this study were to determine the relationship between 25-hydroxyvitamin D [25(OH) D] and glycated hemoglobin (HbA1c) levels in male and female patients with type 2 diabetes mellitus (T2DM). PATIENTS AND

methodsThe participants were adults diagnosed with T2DM recruited from Hebei General Hospital. Patient information and information regarding blood indicators were collected. The subjects were divided into no vitamin D deficiency group [25(OH) D >20 ng/mL] and vitamin D deficiency group [25(OH) D <20 ng/mL], and these groups were then further subdivided into male-only or female-only subgroups. And then, the subjects were divided into male group and female group in different 25(OH) D levels.

resultsHbA1c levels in the vitamin D deficiency group were significantly higher than those in the no vitamin D deficiency group for all subjects. The same was true for female patients but not for male patients. There was no difference in HbA1c levels between male and female patients with T2DM, regardless of 25(OH) D deficiency. A negative correlation existed between 25(OH) D and HbA1c in all subjects, as well as in the male-only and female-only subgroups. Vitamin D deficiency was associated with high HbA1c levels before and after adjusting for confounding factors in all participants and in the female-only subgroup, but not in the male-only subgroup.

conclusionThis study confirmed that vitamin D deficiency was related with high HbA1c levels in patients with T2DM, and this relationship differs between female and male patients.

Indexed as

25-hydroxyvitamin Ddiabetes mellitusglycated hemoglobintype 2

Identifiers

PMID33116736
PMCPMC7585858
OpenAlexW3094328538

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.