Evidence map›Paper›PMID 33116713›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2020

Age, Pulse, Urea and Albumin (APUA) Model: A Tool for Predicting in-Hospital Mortality of Community-Acquired Pneumonia Adapted for Patients with Type 2 Diabetes.

Chun-Ming Ma, Ning Wang, Quan-Wei Su, Ying Yan, Fu-Zai Yin

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Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

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8citing papers in PubMed
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3 · Its place in the literature

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8 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Chun-Ming MaDepartment of Endocrinology, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei, People's Republic of China.
Ning WangDepartment of Internal Medicine, Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Quan-Wei SuDepartment of Internal Medicine, Chengde Medical College, Chengde, Hebei, People's Republic of China.
Ying YanDepartment of Internal Medicine, Chengde Medical College, Chengde, Hebei, People's Republic of China.
Fu-Zai YinDepartment of Endocrinology, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei, People's Republic of China.ORCID 0000-0003-4982-3318

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to develop a tool for predicting in-hospital mortality of community-acquired pneumonia (CAP) in patients with type 2 diabetes (T2DM).

methodsA retrospective study was conducted on 531 CAP patients with T2DM at The First Hospital of Qinhuangdao. The primary outcome was in-hospital mortality. Variables to develop the nomogram were selected using multiple logistic regression analysis. Discrimination was evaluated using receiver operating characteristic (ROC) curve. Calibration was evaluated using the Hosmer-Lemeshow test and calibration plot.

resultsMultiple logistic regression analysis showed that age, pulse, urea and albumin (APUA) were independent risk predictors. Based on these results, we developed a nomogram (APUA model) for predicting in-hospital mortality of CAP in T2DM patients. In the training set, the area under the curve (AUC) of the APUA model was 0.814 (95% CI: 0.770-0.853), which was higher than the AUCs of albumin alone, CURB-65 and Pneumonia Severity Index (PSI) class (

conclusionThe APUA model is a simple and accurate tool for predicting in-hospital mortality of CAP, adapted for patients with T2DM. The predictive performance of the APUA model was better than CURB-65 and PSI class.

Indexed as

albumincommunity-acquired pneumoniamortalitytype 2 diabetes

Identifiers

PMID33116713
PMCPMC7553637

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