Evidence map›Paper›PMID 33116669›Full record

ArticleInfection and drug resistance2020

Effect of Sub-Minimum Inhibitory Concentrations of Tyrosol and EDTA on Quorum Sensing and Virulence of

Shaymaa H Abdel-Rhman, Dina E Rizk, Eman S Abdelmegeed

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Shaymaa H Abdel-RhmanDepartment of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.ORCID 0000-0002-6714-547X
Dina E RizkDepartment of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.ORCID 0000-0003-1609-1878
Eman S AbdelmegeedDepartment of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.ORCID 0000-0002-5817-2572
Mansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPURPOSE: This study investigated the effect of tyrosol and EDTA as anti-quorum-sensing and antivirulence agents against

methodsAnti-quorum activity of sub-minimum inhibitory concentrations (sub-MICs) of tyrosol and EDTA was tested using

resultsTyrosol and EDTA at sub-MICs inhibited the production of violacein pigment. Both compounds inhibited QS molecules production and their associated virulence factors (protease, lipase, lecithinase, and motility) (P≤ 0.05). Besides, the expression levels of QS regulatory genes (

conclusionBoth tyrosol and EDTA can be used to fight

Indexed as

C. violaceumexotoxinsPAO1QS regulatory genesreal-time PCRsignal molecules

Identifiers

PMID33116669
PMCPMC7550211
OpenAlexW3092272422

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.