ArticleNeuropsychiatric disease and treatment2020
Reliability and Validity of THINC-it in Evaluating Cognitive Function of Patients with Bipolar Depression.
Article in Neuropsychiatric disease and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Using the THINC-integrated tool to compare the characteristics of cognitive dysfunction in patients with unipolar and bipolar depression.World journal of psychiatry · 2025Trial
- Cognitive Remediation in Patients With Bipolar Disorder: A Randomized Trial by Sequential tDCS and Navigated rTMS Targeting the Primary Visual Cortex.CNS neuroscience & therapeutics · 2024Trial
- Targeted visual cortex stimulation (TVCS): a novel neuro-navigated repetitive transcranial magnetic stimulation mode for improving cognitive function in bipolar disorder.Translational psychiatry · 2023Trial
- Altered dynamic functional connectivity characteristics in adolescent depression with childhood trauma: a pilot resting-state EEG study.Frontiers in psychology · 2026Article
- Challenges and Opportunities in Using Cognitive Screeners for Adolescents and Young Adults With Bipolar Disorder.Focus (American Psychiatric Publishing) · 2025Article
- The THINC-it tool: temporal sensitivity to change over time.BMC psychiatry · 2024Article
- Article
- Article
- Long term neuropsychiatric consequences in COVID-19 survivors: Cognitive impairment and inflammatory underpinnings fifteen months after discharge.Asian journal of psychiatry · 2023Article
- Validation of the THINC-It Tool for Assessment of Cognitive Impairment in Patients with Bipolar Depression.Neuropsychiatric disease and treatment · 2023Article
- A critical overview of tools for assessing cognition in bipolar disorder.Epidemiology and psychiatric sciences · 2022Review
- Early Effects of Repetitive Transcranial Magnetic Stimulation Combined With Sertraline in Adolescents With First-Episode Major Depressive Disorder.Frontiers in psychiatry · 2022Article
- Depression and Cognitive Impairment: Current Understanding of Its Neurobiology and Diagnosis.Neuropsychiatric disease and treatment · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe THINC-integrated tool (THINC-it) as a brief screening tool can assesses cognitive impairment in patients with major depressive depression (MDD). Here, we aim to evaluate the reliability and validity of the THINC-it in a bipolar depression (BD-D) group in comparison with a healthy control (HC) group. MATERIALS AND
methodsBoth groups were matched according to age, gender, years of education, and IQ. All participants completed the THINC-it test, including Spotter, Symbol Check, Codebreaker, Trails, and the Perceived Deficits Questionnaire for Depression-5-item (PDQ-5-D). The concurrent validity and internal consistency of the THINC-it test were analyzed, and 30 healthy controls were randomly sampled to retest THINC-it to verify the reliability of the THINC-it retest. The correlation between THINC-it and Hamilton Depression Scale (HAMD-17) and Sheehan Disability Scale (SDS) was also analyzed.
resultsFifty-eight patients with BD-D and 61 HCs were included for final analysis. There were significant mean difference (MD) standard errors (SE) between two groups in PDQ-5-D, Spotter and Codebreaker (all
conclusionThis study found that THINC-it can accurately present the cognitive impairment of patients with BD-D. It can be potentially applied in assessing the cognitive function of patients with BD-D although Symbol Check may not accurately reflect the level of cognitive function. The concurrent validity and retest reliability are lower than expected, we need to further increase the sample size to study.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.