Evidence map›Paper›PMID 33116520›Full record

ArticleInternational journal of nanomedicine2020

Ecotoxicity Evaluation of Pristine and Indolicidin-coated Silver Nanoparticles in Aquatic and Terrestrial Ecosystem.

Annarita Falanga, Antonietta Siciliano, Mariateresa Vitiello, Gianluigi Franci, Valentina Del Genio, Stefania Galdiero, Marco Guida, Federica Carraturo, Amir Fahmi, Emilia Galdiero

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 29 citations in OpenAlex.

  1. Nanosystems for delivery of indolicidin peptide.Frontiers in medical technology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Annarita FalangaDepartment of Agricultural Science, University of Naples Federico II, Portici 80055, Italy.ORCID 0000-0001-6538-8585
Antonietta SicilianoDepartment of Biology, University of Naples Federico II, Naples 80100, Italy.
Mariateresa VitielloDepartment of Clinical Pathology, Virology Unit, "San Giovanni di Dio e Ruggi d'Aragona Hospital", Salerno, Italy.
Gianluigi FranciDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana," University of Salerno, Baronissi, Italy.
Valentina Del GenioDepartment of Pharmacy, School of Medicine, University of Naples Federico II, Naples 80134, Italy.ORCID 0000-0003-4227-941X
Stefania GaldieroDepartment of Pharmacy, School of Medicine, University of Naples Federico II, Naples 80134, Italy.ORCID 0000-0002-7849-7024
Marco GuidaDepartment of Biology, University of Naples Federico II, Naples 80100, Italy.ORCID 0000-0001-6805-0408
Federica CarraturoDepartment of Biology, University of Naples Federico II, Naples 80100, Italy.ORCID 0000-0003-0359-3297
Amir Fahmi *Rhein-Waal University of Applied Sciences, Kleve D-47533, Germany.
Emilia Galdiero *Department of Biology, University of Naples Federico II, Naples 80100, Italy.ORCID 0000-0001-8116-0839
University of Naples Federico II · ITOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · ITRhine-Waal University of Applied Sciences · DEUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetallic nanoparticles (NPs) are highly exploited in manufacturing and medical processes in a broad spectrum of industrial applications and in the academic sectors. Several studies have suggested that many metallic nanomaterials including those derived by silver (Ag) are entering the ecosystem to cause significant toxic consequences in cell culture and animal models. However, ecotoxicity studies are still receiving limited attention when designing functionalized and non.-functionalized AgNPs.

objectiveThis study aimed to investigate different ecotoxicological profiles of AgNPs, which were analyzed in two different states: in pristine form uncoated AgNPs and coated AgNPs with the antimicrobial peptide indolicidin. These two types of AgNPs are exploited for a set of different tests using

resultsEcotoxicological studies showed that the most sensitive organism to AgNPs was crustacean

conclusionThe obtained results demonstrate that high ecotoxicity induced by AgNPs is strongly dependent on the surface chemistry, thus the presence of the antimicrobial peptide. This finding opens new avenues to design and fabricate the next generation of metallic nanoparticles to ensure the biosafety and risk of using engineered nanoparticles in consumer products.

Indexed as

EcosystemEcotoxicologyAnimalsAntimicrobial Cationic PeptidesAquatic OrganismsCrustaceaCucumis sativusDaphniaGerminationLactucaLepidiumMetal NanoparticlesSeedsSilverToxicity TestsAntimicrobial Cationic PeptidesindolicidinSilverantimicrobial peptide indolicidinin vivo toxicitynanotoxicologyphytotoxicitysilver nanoparticles

Identifiers

PMID33116520
PMCPMC7585781
OpenAlexW3093349809

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.