Evidence map›Paper›PMID 33116517›Full record

ArticleInternational journal of nanomedicine2020

Therapeutic Potential Assessment of Green Synthesized Zinc Oxide Nanoparticles Derived from Fennel Seeds Extract.

Mohamad S AlSalhi, Sandhanasamy Devanesan, Muhammad Atif, Wedad S AlQahtani, Marcello Nicoletti, Paola Del Serrone

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
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  5. Article
  6. Review
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  8. Review
  9. Phytosynthesis of silver nanoparticles fromSaudi journal of biological sciences · 2022
    Article
  10. Alternatives to Fight Vancomycin-ResistantAntibiotics (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mohamad S AlSalhiResearch Chair in Laser Diagnosis of Cancers, Department of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia.ORCID 0000-0002-4557-8821
Sandhanasamy DevanesanResearch Chair in Laser Diagnosis of Cancers, Department of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia.ORCID 0000-0002-5897-9237
Muhammad AtifResearch Chair in Laser Diagnosis of Cancers, Department of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia.
Wedad S AlQahtaniDepartment of Forensic Sciences, College of Criminal Justice, Naif Arab University for Security Sciences, Riyadh, 11451, Saudi Arabia.
Marcello NicolettiDepartment of Environmental Biology, Sapienza University of Rome, Rome 00185, Italy.
Paola Del SerroneCouncil for Agricultural Research and Economics, Research Center for Zootechnic and Aquaculture, Monterotondo, Rome, 00015, Italy.
King Saud University · SANaif Arab University for Security Sciences · SASapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study the cytotoxic evaluation, antimicrobial and confocal analysis of zinc oxide nanoparticles (ZnO NPs) obtained from a novel plant product fennel (

methodsZnO NPs were analyzed using UV-Vis spectroscopy, XRD, FTIR, TEM and EDX techniques. The MTT cell cytotoxicity assay measured the proliferation and survival of MCF-7 cells treated at different concentrations of FSE-derived ZnO NPs. The antimicrobial activity towards pathogenic bacteria and yeast strains was investigated.

resultsThe UV-Vis spectra showed two peaks at 438 nm and 446 nm, confirming nanoparticle formation. The SEM morphology results showed porous ranging from 23-51 nm. The antitumor activity value (IC

conclusionAs far as it is to our knowledge, this study established, for the first time, the biological activities of biosynthesized ZnO NPs from FSE and their synergistic therapeutic potential.

Indexed as

Anti-Bacterial AgentsCell DeathCell ShapeFoeniculumGreen Chemistry TechnologyHumansMCF-7 CellsMetal NanoparticlesMicrobial Sensitivity TestsPlant ExtractsSeedsStaphylococcus aureusX-Ray DiffractionZinc OxideAnti-Bacterial AgentsPlant ExtractsZinc Oxideantimicrobial activity and therapeutic agentsanti-tumor activityfennel seed extract-derived zinc oxide nanoparticlesgreen nanotechnology

Identifiers

PMID33116517
PMCPMC7585823
OpenAlexW3092955890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.