Evidence map›Paper›PMID 33116506›Full record

ArticleInternational journal of nanomedicine2020

Antibacterial Activity of Chitosan Nanoparticles Against Pathogenic

Fulwah Alqahtani, Fadilah Aleanizy, Eram El Tahir, Hiba Alhabib, Raghad Alsaif, Gamal Shazly, Hajar AlQahtani, Ibrahim Alsarra, Jafar Mahdavi

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Nonantibiotic Treatment of Clinical Multidrug-Resistant Bacterial Isolates Using Chitosan Nanoparticles as a Carrier for the Supernatant of Mesenchymal Stem Cells.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Susceptibility ofVeterinary research forum : an international quarterly journal · 2024
    Article
  11. Article
  12. Therapeutic applications of nanobiotechnology.Journal of nanobiotechnology · 2023
    Review
  13. Review
  14. Antimicrobial Compounds in Food Packaging.International journal of molecular sciences · 2023
    Review
  15. Review
  16. Chitosan loaded RNA polymerase inhibitor nanoparticles increased attenuation in toxin release fromSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fulwah Alqahtani *Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.ORCID 0000-0002-9320-0516
Fadilah Aleanizy *Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.ORCID 0000-0002-6161-3121
Eram El TahirDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.ORCID 0000-0002-6051-4359
Hiba AlhabibDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Raghad AlsaifDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Gamal ShazlyDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Hajar AlQahtaniDepartment of Pharmacy Services, King Abdul-Aziz Medical City, Ministry of National Guard, Health Affairs, Riyadh, Saudi Arabia.ORCID 0000-0002-7719-8209
Ibrahim AlsarraDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.ORCID 0000-0001-5288-5953
Jafar MahdaviSchool of Life Sciences, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe emergence of MATERIALS AND

methodsThe ionic gelation method was used to prepare CNPs of different concentrations. Characterization for their particle size (PZ), polydispersity index (PDI), and zeta potential (ZP) was performed. The anti-microbial activity of CNPs was investigated against 13 WHO

resultsThe average PZ and ZP of the prepared NPs were increased when the concentration of chitosan was increased from 1 to 5 mg/mL and found to be in the range of 193 nm ± 1.9 to 530 nm ± 13.3, and 14 mV ± 0.5 to 20 mV ± 1, respectively. Transmission electron microscopes (TEM) images revealed spherical NPs, and the NPs had a low PDI value of ≤0.27. The formed CNPs produced antibacterial activity against all tested strains, including those resistant to multiple antibiotics, with a minimum inhibitory concentration (MIC

conclusionThe present work findings suggest the potential of the CNPs for the treatment of gonorrhoea.

Indexed as

Anti-Bacterial AgentsBacterial AdhesionChitosanHeLa CellsHumansMicrobial Sensitivity TestsNanoparticlesNeisseria gonorrhoeaeParticle SizeAnti-Bacterial AgentsChitosanadhesionantimicrobialchitosan nanoparticlesN. gonorrhoeae

Identifiers

PMID33116506
PMCPMC7568623

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.