ArticleInternational journal of nanomedicine2020
Synergistic Nanocomposites of Different Antibiotics Coupled with Green Synthesized Chitosan-Based Silver Nanoparticles: Characterization, Antibacterial, in vivo Toxicological and Biodistribution Studies.
Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 11 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 24 citations in OpenAlex.
- Novel biogenic silver nanoparticles produced byNanoscale advances · 2026Article
- Biosynthesized Chitosan-Coated Silver Nanoparticles: Insecticide Activity and Sublethal Effects AgainstBiomolecules · 2025Article
- Synergistic Effect of Silver Nanoparticles with Antibiotics for Eradication of Pathogenic Biofilms.Current pharmaceutical biotechnology · 2024Article
- Advances in silver nanoparticles: a comprehensive review on their potential as antimicrobial agents and their mechanisms of action elucidated by proteomics.Frontiers in microbiology · 2024Review
- Discovery of Anti-MRSA Secondary Metabolites from a Marine-Derived FungusMarine drugs · 2022Article
- Isolation and characterization of two homolog phages infectingFrontiers in microbiology · 2022Article
- Phytochemical, acute toxicity and renal protective appraisal of Ajuga parviflora hydromethanolic leaf extract against CClBMC complementary medicine and therapies · 2021Article
- A mechanistic study on the inhibition of bacterial growth and inflammation by Nerium oleander extract with comprehensive in vivo safety profile.BMC complementary medicine and therapies · 2021Article
- Antimicrobial Actions and Applications of Chitosan.Polymers · 2021Review
- Applications of Silver Nanoparticles in Dentistry: Advances and Technological Innovation.International journal of molecular sciences · 2021Review
- Green Synthesis and Characterization of Carboxymethyl Cellulose Fabricated Silver-Based Nanocomposite for Various Therapeutic Applications.International journal of nanomedicine · 2021Article
Corrections and comments
- Retraction · 2021-12-09Duplication of/in Image · Manipulation of Images ·
- Retracted
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe present study reports chitosan functionalized green synthesized CS-AgNPs, conjugated with amoxicillin (AMX), cefixime (CEF), and levofloxacin (LVX) for safe and enhanced antibacterial activity.
methodsThe CS-AgNPs and conjugates CS-AgNPs+AMX CS-AgNPs+CEF, and CS-AgNPs+LVX were characterized by UV-Vis, FTIR, SEM, TEM, EDX spectroscopy. The size distribution and zeta potential were measured using the dynamic light scattering (DLS) technique. The interaction between CS-AgNPs and antibiotic molecules was also investigated using UV-Vis spectroscopy at the concentrations of 5, 50, 500, and 5000 µM for each antibiotic. Antibacterial activity and synergism were assessed by the Fractional Inhibitory Concentration (FIC) index. The mechanism for synergistic activity was investigated by the detection of hydroxyl species based on the chemiluminescence of luminol. The biocompatibility index (BI) was calculated from IC
resultsThe spherical shape nanocomposites of CS-AgNPs with different antibiotics were prepared with mean size ranges of 80-120 nm. IC
conclusionThe study demonstrates positive attributes of antibiotics-conjugated CS-AgNPs, as a promising antibacterial agent with low toxicity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.