ArticleInternational journal of nanomedicine2020
Preparation of Celery Essential Oil-Based Nanoemulsion by Ultrasonication and Evaluation of Its Potential Anticancer and Antibacterial Activity.
Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 81 citations in OpenAlex.
- Nanoemulsion-Based Enhancement of the Antifungal Activity of Clove and Ginger Essential Oils Combination against Fungi Causing Papaya Rot.Applied biochemistry and biotechnology · 2026Article
- Enhancing the anticancer potential of garlic and lemon essential oils through nanoemulsification: a comparative study.Scientific reports · 2026Article
- Nanoformulation of peppermint (Mentha Piperita L.) and rosemary (Rosmarinus officinalis L.) essential oils: Antibacterial effects.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Myrrh Oil-Based Nanoemulsion Loaded with Curcumin and Insulin: Development, Characterization, and Evaluation of Enhanced Antibacterial and Diabetic Wound-Healing Activity.Pharmaceutics · 2026Article
- Highlight on the synergistic effect of different microemulsion formulations on the virulence determinants of multi-resistant Mycoplasma gallisepticum recovered from poultry.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- In-vitro assessment of anti-breast cancer potential of pumpkin seed oil nanoemulsion with mechanistic insights into cytotoxicity and apoptosis.Scientific reports · 2025Article
- Ultrasonic emulsification of Cananga odorata nanoemulsion formulation for enhancement of herbicidal potential.Scientific reports · 2025Article
- Unveiling the potential anticancer activity of Spirulina maxima extract-nanoemulsion through in vitro and in vivo studies.Scientific reports · 2025Article
- Nanoparticles as Novel Drug Delivery Systems for Cancer Treatment: Current Status and Future Perspectives.Current pharmaceutical design · 2025Review
- Antifungal activity against Candida albicans of methyl 3,5-dinitrobenzoate loaded nanoemulsion.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Defense Mechanisms Induced by Celery Seed Essential Oil against Powdery Mildew Incited byJournal of fungi (Basel, Switzerland) · 2023Article
- Characterization and Determination of the Antibacterial Activity ofAntibiotics (Basel, Switzerland) · 2023Article
- Physicochemical properties of Kakol (Food science & nutrition · 2023Article
- Oxaliplatin-loaded nanoemulsion containingDrug delivery · 2022Article
- Anticancer Applications of Essential Oils Formulated into Lipid-Based Delivery Nanosystems.Pharmaceutics · 2022Review
- Design-of-Experiments (DoE)-Assisted Fabrication of Quercetin-Loaded Nanoemulgel and Its Evaluation against Human Skin Cancer Cell Lines.Pharmaceutics · 2022Article
- Preparation, Characterization and Biological Activities of an Oil-in-Water Nanoemulsion from Fish By-Products and Lemon Oil by Ultrasonication Method.Molecules (Basel, Switzerland) · 2022Article
- Nanomedicine as an Emerging Technology to Foster Application of Essential Oils to Fight Cancer.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Article
- Nanoemulsion as an Effective Inhibitor of Biofilm-forming Bacterial Associated Drug Resistance: An Insight into COVID Based Nosocomial Infections.Biotechnology and bioprocess engineering : BBE · 2022Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPlants have always been a significant source of natural active components with biological properties. Celery seed oil (extracted from
methodsThe therapeutic potential of celery seed oil was investigated through the formulation and testing of a nanoemulsion developed with Tween 80 (a non-ionic surfactant) and the utilization of an ultrasonication technique. Anticancer and apoptotic properties of the formulation were evaluated through MTT and Annexin V-FITC assays. The clonogenic assay aided in the identification of the antiproliferative properties of the formulation on oral squamous cell carcinoma. The antimicrobial study was supported by agar well diffusion assay, membrane integrity test and scanning electron microscopy.
resultsExperiments identified relevant parameters, including optimal surfactant concentration and emulsification time. GC-MS analysis identified various components in the celery oil, but not their biological activities. A sonication time of 20 min resulted in a droplet diameter of 23.4 ± 1.80 nm. The IC
conclusionThe results in this study present celery as a possible constituent for cancer therapeutics and as a candidate for aggressive, yet safe cancer treatment. The celery-based nanoemulsion has the potential to act as a key alternative to standard antibiotic therapy.
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