ArticleInternational journal of nanomedicine2020
Development of an Experimental Dentifrice with Hydroxyapatite Nanoparticles and High Fluoride Concentration to Manage Root Dentin Demineralization.
Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The trial behind it
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Who cites it
9 citing papers in PubMed.
- In vitro evaluation of a novel self-adhesive composite primer modified with nano zinc oxide and hydroxyapatite: antibacterial activity, marginal microleakage, and interfacial elemental analysis.BMC oral health · 2026Article
- Protective effects of herbal toothpastes against dentin erosion: an in vitro study.Scientific reports · 2026Article
- Nanohydroxyapatite in dentistry: A comprehensive review.The Saudi dental journal · 2023Article
- Potential Beneficial Effects of Hydroxyapatite Nanoparticles on Caries Lesions In Vitro-A Review of the Literature.Dentistry journal · 2023Review
- Development of Root Caries Prevention by Nano-Hydroxyapatite Coating and Improvement of Dentin Acid Resistance.Materials (Basel, Switzerland) · 2022Article
- Nano-Hydroxyapatite (nHAp) in the Remineralization of Early Dental Caries: A Scoping Review.International journal of environmental research and public health · 2022Article
- The use of hydroxyapatite toothpaste to prevent dental caries.Odontology · 2022Review
- Comparative Study of Anti-COVID Mouthwash and Remineralization Agents on Dentinal Tubular Occlusion: AnJournal of International Society of Preventive & Community DentistryArticle
- Morphological & chemo mechanical analysis of exposed cervical dentin treated with three different desensitizing pastes (comparative in vitro study).Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh-fluoride dentifrice is used to manage root caries, but there is no evidence whether its association with nanohydroxyapatite could provide an additional protection for root caries. Therefore, this study aimed to develop and evaluate the effect of an experimental dentifrice with high fluoride (F MATERIALS AND
methodsAfter formulation of dentifrices, root dentin specimens were randomly assigned to six groups (n = 10) using different dentifrice treatments: placebo; nano-HA without F
resultsThe experimental dentifrices were stable and had no cytotoxicity. Regarding dentin demineralization, the placebo group significantly increased ΔS compared to all other treatment groups (p<0.001). The dentifrices containing 5,000 µg F
conclusionThe findings of this study suggest that nano-HA reduced dentin demineralization, and dentifrice with 5,000 µg F
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Registered trials
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