ArticleNature2020
Parallel ascending spinal pathways for affective touch and pain.
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Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 148 papers.
0numbers the graph read from it
0cells of the map it votes in
148citing papers in PubMed
14.3field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
148 citing papers in PubMed, 268 citations in OpenAlex.
- Widespread Pressure Delivered by a Weighted Blanket Reduces Chronic Pain: A Randomized Controlled Trial.The journal of pain · 2022Trial
- Progress in pain mechanisms and management.Signal transduction and targeted therapy · 2026Review
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- Virtual reality versus companion-delivered therapeutic touch for reducing pain and anxiety during suturing: a randomized controlled trial.International journal of emergency medicine · 2026Article
- Distinct Role of Specialized Cutaneous Schwann Cell Network in Acute and Chronic Pain Sensation.Neuroscience bulletin · 2026Article
- The Intraplantar CFA Inflammatory Pain Model Incompletely Captures Pain Comorbidities Across Sexes.Journal of neuroscience research · 2026Article
- Phase-Separated Nanoarchitecture of Adhesion-Cytoskeleton Force Coupling Reforms Nuclear Spatiotemporal Posture Conformation and Mechanotransduction of Osteosarcoma on Biofunctional Microarrays.Advanced healthcare materials · 2026Article
- Targeting GCell reports. Medicine · 2026Article
- Synchrony within Aβ mechanoreceptor subtypes governs signal propagation to primary somatosensory cortex.The Journal of physiology · 2026Article
- Role of PBN-CeA Circuit in Paclitaxel-Induced Neuropathic Pain and Negative Emotions.CNS neuroscience & therapeutics · 2026Article
- ParabrachialProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Article
- Deep Cellular and Spatial Profiling of the Mouse Spinal Cord Reveals Sex-Specific Neuron Types and the Ascending Projection Neuron Repertoire.bioRxiv : the preprint server for biology · 2026Article
- Article
- Modulation of pain by affective touch: effects of childhood trauma, depression, chronic pain, and spinal segment.The Journal of physiology · 2026Article
- A Tac1-Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- NaThe Journal of comparative neurology · 2026Article
- Descending inhibitory rostral ventromedial medulla neurons cause widespread antinociception and contribute to the pain-inhibits-pain phenomenon.Nature communications · 2026Article
- Review
88 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 3 institutions in 3 countries.
Seungwon ChoiDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Junichi HachisukaDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.
Matthew A BrettDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Alexandra R MageeDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Yu OmoriDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.
Noor-Ul-Aine IqbalDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Dawei ZhangDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Michelle M DeLisleDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-8475-7411
Rachel L WolfsonDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Ling BaiDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Celine SantiagoDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Shiaoching GongThe Laboratory of Molecular Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
Martyn GouldingMolecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Nathaniel HeintzThe Laboratory of Molecular Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
H Richard KoerberDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.
Sarah E RossDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.
David D GintyDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA. david_ginty@hms.harvard.edu.ORCID http://orcid.org/0000-0001-9723-8530
Howard Hughes Medical Institute · USUniversity of Pittsburgh · USSalk Institute for Biological Studies · US
Funding
Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0MSpinal circuits for mechanical itch and light touchR35NS111643 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Martyn D Goulding · 2019 to 2026
$9.7MInvestigating the Neural Circuits of ItchR01AR063772 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI H Richard Koerber, Sarah Elizabeth Ross · 2013 to 2026
$6.9MElucidating Cutaneous Mechanosensory Circuits, from Development to DiseaseR35NS097344 · NINDS · HARVARD MEDICAL SCHOOL · PI GINTY, DAVID D · 2016 to 2023
$6.8MSpinal Cord Nociceptive Circuits that Deliver Outputs to the Brain to Initiate PainR01AT011447 · NCCIH · HARVARD MEDICAL SCHOOL · PI DRUGOWITSCH, JAN, GINTY, DAVID D · 2020 to 2024
$5.3MMouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI POMEROY, SCOTT LOREN · 2016 to 2020
$5.2MMolecular genetic dissection of the spinal microcircuits of wind-upR01NS096705 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOERBER, H RICHARD, ROSS, SARAH ELIZABETH · 2016 to 2025
$5.1MCharacterization of epithelial-neural communicationR01AR069951 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALBERS, KATHRYN MARIE, DAVIS, BRIAN M · 2016 to 2020
$2.8MPathways to Mentorship and Research: Training the Next Generation Physician-ScientistsR25AI147393 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI VYAS, JATIN M · 2019 to 2024
$1.8MHoward Hughes Medical InstituteNCCIH NIH HHS R01 AT011447NIAID NIH HHS R25 AI147393NIAMS NIH HHS R01 AR063772NIAMS NIH HHS R01 AR069951NICHD NIH HHS U54 HD090255NIGMS NIH HHS T32 GM007753NIH HHS AT011447NINDS NIH HHS R01 NS096705NINDS NIH HHS R35 NS097344NINDS NIH HHS R35 NS111643
Abstract
The anterolateral pathway consists of ascending spinal tracts that convey pain, temperature and touch information from the spinal cord to the brain
Indexed as
Neural PathwaysAnimalsAxonsFemaleMaleMechanotransduction, CellularMicePainPhilosophyReceptors, G-Protein-CoupledSensory Receptor CellsSkinSpinal CordSynapsesTouchGpr83 protein, mouseReceptors, G-Protein-Coupled
Identifiers
What OpenQuestion holds
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.