ArticleNature2020
High-depth African genomes inform human migration and health.
Erratum issuedAbstract readHistorical Article
In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 226 papers, 8 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
226citing papers in PubMed, 8 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
226 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans.Genome medicine · 2024Pooled it
- Genome-wide association study meta-analysis of blood pressure traits and hypertension in sub-Saharan African populations: an AWI-Gen study.Nature communications · 2023Pooled it
- Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study.The Lancet. Neurology · 2023Pooled it
- Genome-wide association study of esophageal squamous cell cancer identifies shared and distinct risk variants in African and Chinese populations.American journal of human genetics · 2023Pooled it
- Identifying the genetic causes of developmental disorders and intellectual disability in Africa: a systematic literature review.Frontiers in genetics · 2023Pooled it
- A genome-wide association study for rheumatoid arthritis replicates previous HLA and non-HLA associations in a cohort from South Africa.Human molecular genetics · 2022Pooled it
- Polygenic Prediction of Type 2 Diabetes in Africa.Diabetes care · 2022Pooled it
- Guideline for feedback of individual genetic research findings for genomics research in Africa.BMJ global health · 2022Guideline
- Mapping long-read sequences to a complete reference genome reveals uncaptured variants across the β-Globin cluster in Africans with sickle cell disease.HGG advances · 2026Article
- Resolving missing human polymorphic inversions and other complex variants from ultralong read data.Genome research · 2026Article
- A Cohort Study on Incidence and Factors Associated With Adverse Drug Reactions of Enalapril in Lusaka, Zambia.Pharmacology research & perspectives · 2026Article
- High KIR diversity in Uganda and Botswana children living with HIV.Human immunology · 2026Article
- Emerging trends in the global burden of colorectal cancer.Nature reviews. Clinical oncology · 2026Review
- Extending genome-wide association studies to admixed cohorts with high degrees of relatedness.Nature genetics · 2026Article
- Article
- Immunological Determinants of Oncogenic Virus-Driven Cancers in Africa: Mechanisms, Co-Infections and Public Health Challenges.Pathogens (Basel, Switzerland) · 2026Review
- Precision oncology without borders: the role of biobanking in integrating Africa's genetic diversity into global genomic research.NPJ precision oncology · 2026Review
- They build science capacity in Africa for Africa.Nature methods · 2026Article
- Advancing global genomic equity: making a case for national genome projects in Africa.Nature communications · 2026Article
- Revisiting the African mtDNA landscape through complete mitochondrial genomes.Communications biology · 2026Article
166 more citing papers are in PubMed but not listed here.
Corrections and comments
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- Erratum issued
Authors and funding
34 authors.
Ananyo ChoudhurySydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Shaun AronSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Laura R BotiguéCenter for Research in Agricultural Genomics (CRAG), Plant and Animal Genomics Program, CSIC-IRTA-UAB-UB, Barcelona, Spain.
Dhriti SenguptaSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Gerrit BothaComputational Biology Division and H3ABioNet, Department of Integrative Biomedical Sciences, IDM, University of Cape Town, Cape Town, South Africa.
Taoufik BensellakSystem and Data Engineering Team, Abdelmalek Essaadi University, ENSA, Tangier, Morocco.ORCID http://orcid.org/0000-0002-6151-6276
Gordon WellsCentre for Proteomic and Genomic Research (CPGR), Cape Town, South Africa.
Judit KumuthiniCentre for Proteomic and Genomic Research (CPGR), Cape Town, South Africa.
Daniel ShrinerCenter for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-1928-5520
Yasmina J FakimDepartment of Agriculture and Food Science, Faculty of Agriculture, University of Mauritius, Reduit, Mauritius.
Anisah W GhoorahDepartment of Digital Technologies,Faculty of Information, Communication & Digital Technologies, University of Mauritius, Reduit, Mauritius.ORCID http://orcid.org/0000-0001-8273-6000
Eileen DarengDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-0802-419X
Trust OdiaCovenant University Bioinformatics Research (CUBRe), Covenant University, Ota, Nigeria.
Oluwadamilare FalolaCovenant University Bioinformatics Research (CUBRe), Covenant University, Ota, Nigeria.
Ezekiel AdebiyiCovenant University Bioinformatics Research (CUBRe), Covenant University, Ota, Nigeria.
Scott HazelhurstSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-0581-149X
Gaston MazanduComputational Biology Division and H3ABioNet, Department of Integrative Biomedical Sciences, IDM, University of Cape Town, Cape Town, South Africa.
Oscar A NyangiriCollege of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.ORCID http://orcid.org/0000-0003-2741-2921
Mamana MbiyavangaComputational Biology Division and H3ABioNet, Department of Integrative Biomedical Sciences, IDM, University of Cape Town, Cape Town, South Africa.
Alia BenkahlaLaboratory of Bioinformatics, Biomathematics and Biostatistics (BIMS), Institute Pasteur of Tunis, Tunis, Tunisia.
Samar K KassimMedical Biochemistry and Molecular Biology Department, Faculty of Medicine, Ain Shams University, Abbaseya, Cairo, Egypt.ORCID http://orcid.org/0000-0002-4359-6620
Nicola MulderComputational Biology Division and H3ABioNet, Department of Integrative Biomedical Sciences, IDM, University of Cape Town, Cape Town, South Africa.
Sally N AdebamowoDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, University of Maryland Baltimore, Baltimore, MD, USA.
Emile R ChimusaDivision of Human Genetics, Department of Pathology, Faculty of Health Sciences, Institute for Infectious, Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Donna MuznyHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Ginger MetcalfHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Richard A GibbsHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
TrypanoGEN Research Group
Charles RotimiCenter for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-5759-053X
Michèle RamsaySydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-4156-4801
H3Africa Consortium
Adebowale A AdeyemoCenter for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. adeyemoa@mail.nih.gov.ORCID http://orcid.org/0000-0002-3105-3231
Zané LombardDivision of Human Genetics, National Health Laboratory Service, and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. zane.lombard@wits.ac.za.ORCID http://orcid.org/0000-0002-7997-2616
Neil A HanchardDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA. hanchard@bcm.edu.ORCID http://orcid.org/0000-0003-1925-2665
Funding
The Human Genome Sequencing CenterU54HG003273 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI GIBBS, RICHARD A · 2004 to 2015
$341.3MH3ABioNet: informatics solutions for H3AfricaU24HG006941 · NHGRI · UNIVERSITY OF CAPE TOWN · PI MULDER, NICOLA · 2017 to 2021
$12.9MShared Core: Biobanking, Bioinformatics and Data ManagementU54HG006938 · NHGRI · WITS HEALTH CONSORTIUM (PTY), LTD · PI RAMSAY, MICHELE MICHELE · 2012 to 2022
$12.2MPhenotyping and BioarchivingU54AI110398 · NIAID · BOTSWANA BAYLOR CHILD/CLINCAL CTR/EXCELL · PI MATSHABA, MOGOMOTSI SANDY · 2014 to 2021
$8.9MSickle Africa Data Coordinating CenterU24HL135600 · NHLBI · UNIVERSITY OF CAPE TOWN · PI MULDER, NICOLA, WONKAM, AMBROISE · 2017 to 2025
$8.6MH3Africa Kidney Disease Research NetworkU54HG006939 · NHGRI · NOGUCHI MEMORIAL INSTITUTE / MEDICAL RES · PI ADU, DWOMOA, OJO, AKINLOLU OLUSEUN · 2012 to 2017
$6.1MAfrican Collaborative Center for Microbiome and Genomics Research (ACCME)U54HG006947 · NHGRI · INSTITUTE OF HUMAN VIROLOGY · PI ADEBAMOWO, CLEMENT ADEBAYO · 2013 to 2018
$5.7MH3Africa Kidney Disease Research Network- Collaborative CentersU54DK116913 · NIDDK · COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA · PI ADU, DWOMOA, OJO, AKINLOLU OLUSEUN · 2017 to 2021
$4.1MClinical and genetic studies of hereditary neurological disorders in MaliU01HG007044 · NHGRI · UNIV OF SCIENCES, TECH & TECH OF BAMAKO · PI LANDOURE, GUIDA · 2013 to 2022
$3.1MDeciphering Developmental Disorders in Africa (DDD-Africa) - Evaluating Clinical Exome Sequencing in an African SettingU01MH115483 · NIMH · WITS HEALTH CONSORTIUM (PTY), LTD · PI LOMBARD, ZANE · 2017 to 2021
$1.3MHearing Impairment Genetics Studies in Africa (HI-GENES Africa)U01HG009716 · NHGRI · UNIVERSITY OF CAPE TOWN · PI WONKAM, AMBROISE · 2017 to 2021
$1.2MExploring Perspectives on Genomics and Sickle Cell Public Health InterventionsU01HG007459 · NHGRI · UNIVERSITY OF CAPE TOWN · PI WONKAM, AMBROISE · 2013 to 2016
$622kNHGRI NIH HHS U01 HG007044NHGRI NIH HHS U01 HG007459NHGRI NIH HHS U01 HG009716NHGRI NIH HHS U24 HG006941NHGRI NIH HHS U54 HG003273NHGRI NIH HHS U54 HG006938NHGRI NIH HHS U54 HG006939NHGRI NIH HHS U54 HG006947NHLBI NIH HHS U24 HL135600NIAID NIH HHS U54 AI110398NIDDK NIH HHS U54 DK116913NIMH NIH HHS U01 MH115483Wellcome TrustWellcome Trust 099310/Z/12/Z
Abstract
The African continent is regarded as the cradle of modern humans and African genomes contain more genetic variation than those from any other continent, yet only a fraction of the genetic diversity among African individuals has been surveyed
Indexed as
Genetic VariationGenomicsHealthHuman MigrationAfricaDatasets as TopicDNA RepairFemaleGene FlowGenetics, MedicalGenetics, PopulationGenome, HumanHistory, AncientHumansImmunityLanguage
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.