ArticleScientific reports2020
Diagnostic accuracy of "sweeping" method compared to conventional sampling in rapid urease test for Helicobacter pylori detection in atrophic mucosa.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Efficacy of swab-based RUT in detecting H. pylori infection: a systematic review and meta-analysis.BMC gastroenterology · 2026Pooled it
- Social determinants of health andFrontiers in public health · 2025Pooled it
- Molecular Characterization and Genetic Diversity ofDiagnostics (Basel, Switzerland) · 2026Article
- Mucosal Brush Sampling Increases theGut and liver · 2026Article
- Review
- Diagnosis and treatment ofFuture microbiology · 2025Review
- The Potential Role of the Rapid Urease Test with the Sweeping Method in the Gray Zone of the Urea Breath Test afterGut and liver · 2025Article
- Evaluation of the Rapid Urease Test (RUT) Device for Rapid Diagnosis ofMicroorganisms · 2025Article
- Validity of rapid urease test using swab of gastric mucus to mucosal forceps and 13 C-urease breath test: a multicenter prospective observational study.BMC gastroenterology · 2024Observational
- Essential Oils: Chemistry and Pharmacological Activities-Part II.Biomedicines · 2024Review
- Dysbiosis by Eradication ofMicroorganisms · 2023Article
- Colorimetric Detection of Urease-Producing Microbes Using an Ammonia-Responsive Flexible Film Sensor.Biosensors · 2022Article
- Helicobacter pylori Infection, Its Laboratory Diagnosis, and Antimicrobial Resistance: a Perspective of Clinical Relevance.Clinical microbiology reviews · 2022Review
- Diagnostic approach toAnnals of gastroenterologyReview
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the rapid urease test (RUT) is a simple method for detecting Helicobacter pylori (H. pylori) infection, it requires sufficient biopsy samples and its sensitivity varies depending on the site and condition of H. pylori infection. We compared the diagnostic performance of a "sweeping method" for H. pylori detection with the conventional biopsy sampling method in atrophic gastric conditions which can reduce RUT accuracy. This prospective study included 279 patients who underwent upper endoscopy to determine the presence of H. pylori infection. Gastric mucosa of both the antrum and the corpus were swabbed, and we named this method the "sweeping method". Biopsy sampling for the conventional method, histologic evaluation, and polymerase chain reaction were performed at the same time. The sensitivity, specificity, and accuracy of the sweeping method were 0.941, 0.826, and 0.903, respectively, compared to 0.685, 0.859, and 0.742, respectively, for the conventional biopsy method. The area under the receiver operating curve for the sweeping method was 0.884 versus 0.772 for the conventional method (P < 0.001). The sweeping method had a faster detection time than the conventional method. Compared to conventional biopsy sampling, the sweeping method with the RUT provided higher sensitivity and accuracy for the detection of H. pylori, with a faster detection time.
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