Evidence map›Paper›PMID 33116234›Full record

ArticleScientific reports2020

A direct comparison of natural and acoustic-radiation-force-induced cardiac mechanical waves.

Lana B H Keijzer, Annette Caenen, Jason Voorneveld, Mihai Strachinaru, Daniel J Bowen, Jens van de Wouw, Oana Sorop, Daphne Merkus, Dirk J Duncker, Antonius F W van der Steen and 3 more

Open access · goldAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Lana B H KeijzerDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands. l.b.h.keijzer@erasmusmc.nl.
Annette CaenenDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands. annette.caenen@ugent.be.
Jason VoorneveldDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Mihai StrachinaruDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Daniel J BowenDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Jens van de WouwDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Oana SoropDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Daphne MerkusDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Dirk J DunckerDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Antonius F W van der SteenDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Nico de JongDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Johan G BoschDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Hendrik J VosDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Erasmus University Rotterdam · NLErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural and active shear wave elastography (SWE) are potential ultrasound-based techniques to non-invasively assess myocardial stiffness, which could improve current diagnosis of heart failure. This study aims to bridge the knowledge gap between both techniques and discuss their respective impacts on cardiac stiffness evaluation. We recorded the mechanical waves occurring after aortic and mitral valve closure (AVC, MVC) and those induced by acoustic radiation force throughout the cardiac cycle in four pigs after sternotomy. Natural SWE showed a higher feasibility than active SWE, which is an advantage for clinical application. Median propagation speeds of 2.5-4.0 m/s and 1.6-4.0 m/s were obtained after AVC and MVC, whereas ARF-based median speeds of 0.9-1.2 m/s and 2.1-3.8 m/s were reported for diastole and systole, respectively. The different wave characteristics in both methods, such as the frequency content, complicate the direct comparison of waves. Nevertheless, a good match was found in propagation speeds between natural and active SWE at the moment of valve closure, and the natural waves showed higher propagation speeds than in diastole. Furthermore, the results demonstrated that the natural waves occur in between diastole and systole identified with active SWE, and thus represent a myocardial stiffness in between relaxation and contraction.

Indexed as

Elasticity Imaging TechniquesMyocardial ContractionAnimalsFemaleHeartSwine

Identifiers

PMID33116234
PMCPMC7595170
OpenAlexW3096255527

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.