Evidence map›Paper›PMID 33116229›Full record

ArticleScientific reports2020

Detection of functional deterioration in glaucoma by trend analysis using comprehensive overlapping clusters of locations.

Stuart K Gardiner, Steven L Mansberger

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stuart K GardinerDevers Eye Institute, Legacy Research Institute, 1225 NE 2nd Ave, Portland, OR, 97232, USA. sgardiner@deverseye.org.
Steven L MansbergerDevers Eye Institute, Legacy Research Institute, 1225 NE 2nd Ave, Portland, OR, 97232, USA.

Funding

Functional Testing for GlaucomaR01EY020922 · NEI · LEGACY EMANUEL HOSPITAL AND HEALTH CENTER · PI GARDINER, STUART · 2011 to 2021
$3.2M
NEI NIH HHS R01 EY020922NEI NIH HHS R01EY020922
6 · The paper itself

Abstract

Detecting rapid visual field deterioration is crucial for individuals with glaucoma. Cluster trend analysis detects visual field deterioration with higher sensitivity than global analyses by using predefined non-overlapping subsets of visual field locations. However, it may miss small defects that straddle cluster borders. This study introduces a comprehensive set of overlapping clusters, and assesses whether this further improves progression detection. Clusters were defined as locations from where ganglion cell axons enter the optic nerve head within a θ° wide sector, centered at 1º intervals, for various θ. Deterioration in eyes with or at risk of glaucomatous visual field loss was "detected" if ≥ N

Indexed as

Visual FieldsVisual Field TestsAdultAgedAged, 80 and overFemaleGlaucomaHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID33116229
PMCPMC7595105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.