Trial reportScientific reports2020
The role of anterior and posterior insula in male genital response and in visual attention: an exploratory multimodal fMRI study.
Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Brain Activation Patterns during Sexual Arousal: A Comparative Time-Course Functional Magnetic Resonance Imaging Study in Postoperative Female-to-Male Transgender Individuals, Cisgender Men, and Premenopausal Women.The world journal of men's health · 2026Article
- The interplay between functional connectivity of medial and lateral visual networks, behavioral measures, and oxytocin receptor gene polymorphism (rs2254298) in autism.European child & adolescent psychiatry · 2025Article
- Altered domain-specific striatal functional connectivity in patients with Parkinson's disease and urinary symptoms.Journal of neural transmission (Vienna, Austria : 1996) · 2024Article
- Altered Functional Connectivity of Large-Scale Brain Networks in Psychogenic Erectile Dysfunction Associated with Cognitive Impairments.Neuropsychiatric disease and treatment · 2023Article
- The Brain Activation-Based Sexual Image Classifier (BASIC): A Sensitive and Specific fMRI Activity Pattern for Sexual Image Processing.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Neural substrates of brand equity: applying a quantitative meta-analytical method for neuroimage studies.Heliyon · 2022Article
- Breath chemical markers of sexual arousal in humans.Scientific reports · 2022Article
- The Reproductive Functions of the Human Brain Regions: A Systematic Review.Journal of human reproductive sciencesReview
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several studies highlighted the role of insula on several functions and in sexual behavior. This exploratory study examines the relationships among genital responses, brain responses, and eye movements, to disentangle the role played by the anterior and posterior insula during different stages of male sexual response and during visual attention to sexual stimuli. In 19 healthy men, fMRI, eye movement, and penile tumescence data were collected during a visual sexual stimulation task. After a whole-brain analysis comparing neutral and sexual clips and confirming a role for the bilateral insulae, we selected two bilateral seed regions in anterior and posterior insula for functional connectivity analysis. Single-ROI-GLMs were run for the FC target regions. Single-ROI-GLMs were performed based on areas to which participants fixate: "Faces", "Genitals," and "Background" with the contrast "Genitals > Faces". Single-ROI-GLMs with baseline, onset, and sustained PT response for the sexual clips were performed. We found stronger effects for the posterior than the anterior insula. In the target regions of the posterior insula, we found three different pathways: the first involved in visual attention, onset of erection, and sustained erection; the second involved only in the onset of erection, and the third limited to sustained erection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.