Evidence map›Paper›PMID 33116012›Full record

ReviewInternal medicine (Tokyo, Japan)2021

Recurrence of Acute Lymphoblastic Leukemia with Bone Marrow Necrosis: A Case Report and Review of the Literature on the MRI Features of Bone Marrow Necrosis.

Naonori Harada, Mitsutaka Nishimoto, Aya Ikemoto, Hiroshi Okamura, Shiro Koh, Satoru Nanno, Yasuhiro Nakashima, Hideo Koh, Takahiko Nakane, Yuko Kuwae and 3 more

Open access · diamondAbstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Naonori HaradaDepartment of Hematology, Graduate School of Medicine, Osaka City University, Japan.
Mitsutaka NishimotoDepartment of Hematology, Graduate School of Medicine, Osaka City University, Japan.
Aya IkemotoDepartment of Clinical Laboratory, Osaka City University Hospital, Japan.
Hiroshi OkamuraDepartment of Hematology, Graduate School of Medicine, Osaka City University, Japan.
Shiro KohDepartment of Hematology, Graduate School of Medicine, Osaka City University, Japan.
Satoru NannoDepartment of Hematology, Graduate School of Medicine, Osaka City University, Japan.
Yasuhiro NakashimaDepartment of Hematology, Graduate School of Medicine, Osaka City University, Japan.
Hideo KohDepartment of Hematology, Graduate School of Medicine, Osaka City University, Japan.
Takahiko NakaneDepartment of Hematology, Graduate School of Medicine, Osaka City University, Japan.
Yuko KuwaeDepartment of Diagnostic Pathology, Graduate School of Medicine, Osaka City University, Japan.
Masahiko OhsawaDepartment of Diagnostic Pathology, Graduate School of Medicine, Osaka City University, Japan.
Masayuki HinoDepartment of Hematology, Graduate School of Medicine, Osaka City University, Japan.
Hirohisa NakamaeDepartment of Hematology, Graduate School of Medicine, Osaka City University, Japan.
Osaka City University · JPOsaka City University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone marrow necrosis (BMN) is a rare but important complication of hematological malignancies. We report the case of a 52-year-old male patient with a recurrence of acute lymphoblastic leukemia (ALL) accompanied by BMN. After re-induction therapy, bone marrow aspiration (BMA) and biopsy from the iliac bone showed necrotic cells and eosinophilic debris, respectively. Magnetic resonance imaging (MRI) showed heterogeneous signals in the bilateral iliac bone, possibly reflecting various stages of BMN. BMA from the sternum eventually revealed the recurrence of ALL after a few weeks. Comprehensive assessments, including MRI and repeated bone marrow tests, are required when evaluating the underlying hematological malignancies of patients with BMN.

Indexed as

Hematologic DiseasesPrecursor Cell Lymphoblastic Leukemia-LymphomaBone MarrowHumansMagnetic Resonance ImagingMaleMiddle AgedNecrosisacute lymphoblastic leukemiabone marrow aspiration from the sternumbone marrow necrosismagnetic resonance imaging

Identifiers

PMID33116012
PMCPMC8079900
OpenAlexW3094698392

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.