ArticleScience translational medicine2020
Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity.
Article in Science translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 46 citations in OpenAlex.
- Enhancing exosomes efficacy with engineered nanozymes for a multi-targeted combination strategy in osteoarthritis treatment.Materials today. Bio · 2026Article
- Osteoarthritis and depression a bidirectional TwoSample Mendelian randomization study on genetic causal association.BMC musculoskeletal disorders · 2026Article
- Gene Therapy for the Treatment of Osteoarthritis: Advances and Prospective.Current pharmaceutical design · 2026Review
- Therapeutic potential of IκB kinase epsilon inhibition in preventing meniscal degeneration of early osteoarthritis.Bone & joint research · 2025Article
- Dialdehyde Starch Cross-Linked Collagen with Heparin Conjugation: Characterization and Feasibility Study for Osteochondral Tissue Repair.Gels (Basel, Switzerland) · 2025Article
- Dynamic-covalent hybrid hydrogels with cartilaginous immune microenvironment temporally regulating meniscus regeneration.Bioactive materials · 2025Article
- MAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- The Mkx- TGF-β pathway induced the development of the myodural bridge complex in SD rats.Frontiers in cell and developmental biology · 2025Article
- Injectable decellularized Wharton's jelly hydrogel containing CD56Materials today. Bio · 2024Article
- Meniscus gene expression profiling of inner and outer zone meniscus tissue compared to cartilage and passaged monolayer meniscus cells.Scientific reports · 2024Article
- Silk fibroin hydrogel adhesive enables sealed-tight reconstruction of meniscus tears.Nature communications · 2024Article
- Single-cell RNA sequencing in osteoarthritis.Cell proliferation · 2023Review
- Mocetinostat activates Krüppel-like factor 4 and protects against tissue destruction and inflammation in osteoarthritis.JCI insight · 2023Article
- Article
- A comparative study on various cell sources for constructing tissue-engineered meniscus.Frontiers in bioengineering and biotechnology · 2023Article
- RNA-binding proteins that are highly expressed and enriched in healthy cartilage but suppressed in osteoarthritis.Frontiers in cell and developmental biology · 2023Article
- Biomimicking design of artificial periosteum for promoting bone healing.Journal of orthopaedic translation · 2022Review
- Meniscus surface texture is associated with degenerative changes in biological and biomechanical properties.Scientific reports · 2022Article
- Krüppel-like factor-4 and Krüppel-like factor-2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritis.Annals of the rheumatic diseases · 2022Article
- Meniscus repair: up-to-date advances in stem cell-based therapy.Stem cell research & therapy · 2022Review
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
Meniscus tears are common knee injuries and a major osteoarthritis (OA) risk factor. Knowledge gaps that limit the development of therapies for meniscus injury and degeneration concern transcription factors that control the meniscus cell phenotype. Analysis of RNA sequencing data from 37 human tissues in the Genotype-Tissue Expression database and RNA sequencing data from meniscus and articular cartilage showed that transcription factor Mohawk (MKX) is highly enriched in meniscus. In human meniscus cells, MKX regulates the expression of meniscus marker genes, OA-related genes, and other transcription factors, including Scleraxis (
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Registered trials
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