Evidence map›Paper›PMID 33115922›Full record

ArticleOccupational and environmental medicine2021

Lung cancer risk in painters: results from the SYNERGY pooled case-control study consortium.

Neela Guha, Liacine Bouaoun, Hans Kromhout, Roel Vermeulen, Thomas Brüning, Thomas Behrens, Susan Peters, Véronique Luzon, Jack Siemiatycki, Mengting Xu and 39 more

Open access · hybridAbstract read
In one paragraph

Article in Occupational and environmental medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Etiology of lung cancer: Evidence from epidemiologic studies.Journal of the National Cancer Center · 2022
    Review
  6. Lung Cancer in the French West Indies: Role of Sugarcane Work and Other Occupational Exposures.International journal of environmental research and public health · 2022
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors at 20 institutions in 21 countries.

Neela GuhaInternational Agency for Research on Cancer, Lyon, France.ORCID 0000-0003-3991-4662
Liacine BouaounInternational Agency for Research on Cancer, Lyon, France.
Hans KromhoutInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0002-4233-1890
Roel VermeulenInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
Thomas BrüningInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University (IPA), Bochum, Germany.
Thomas BehrensInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University (IPA), Bochum, Germany.
Susan PetersInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
Véronique LuzonInternational Agency for Research on Cancer, Lyon, France.
Jack SiemiatyckiDepartment of Social and Preventive Medicine, University of Montreal, Montreal, Quebec, Canada.ORCID 0000-0002-9042-8582
Mengting XuDepartment of Social and Preventive Medicine, University of Montreal, Montreal, Quebec, Canada.ORCID 0000-0002-6751-1986
Benjamin KendziaInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University (IPA), Bochum, Germany.
Pascal GuenelCenter for Research in Epidemiology and Population Health (CESP), Exposome and Heredity team, Inserm U1018, University Paris-Saclay, Villejuif, France.ORCID 0000-0002-8359-518X
Danièle LuceUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Pointe-à-Pitre, France.ORCID 0000-0002-1708-4584
Stefan KarraschInstitute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Inner City Clinic, University Hospital of Munich, Ludwig-Maximilians-Universität; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munchen, Germany.
Heinz-Erich WichmannInstitut für Medizinische Informatik Biometrie Epidemiologie, Ludwig Maximilians University, Munich, Germany.
Dario ConsonniEpidemiology Unit, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy.ORCID 0000-0002-8935-3843
Maria Teresa LandiDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Neil E CaporasoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Per GustavssonInstitute of Environmental Medicine, Unit of Occupational Medicine, Karolinska Institute, Stockholm, Sweden.ORCID 0000-0003-2221-8599
Nils PlatoInstitute of Environmental Medicine, Unit of Occupational Medicine, Karolinska Institute, Stockholm, Sweden.
Franco MerlettiDepartment of Medical Sciences, Cancer Epidemiology Unit, University of Turin, Turin, Italy.
Dario MirabelliDepartment of Medical Sciences, Cancer Epidemiology Unit, University of Turin, Turin, Italy.
Lorenzo RichiardiDepartment of Medical Sciences, Cancer Epidemiology Unit, University of Turin, Turin, Italy.
Karl-Heinz JöckelInstitute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany.
Wolfgang AhrensLeibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.
Hermann PohlabelnLeibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.
Lap Ah TseJC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Ignatius Tak-Sun YuJC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Adonina TardónDepartment of Public Health, University of Oviedo, ISPA and CIBERESP, Oviedo, Spain.
Paolo BoffettaStony Brook Cancer Center, Stony Brook University, Stony Brook, New York, USA.ORCID 0000-0002-3811-2791
David ZaridzeDepartment of Cancer Epidemiology and Prevention, N.N. Blokhin National Research Centre of Oncology, Moscow, Russian Federation.
Andrea 't MannetjeCentre for Public Health Research, Massey University, Wellington, New Zealand.
Neil PearceDepartment of Non-communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.ORCID 0000-0002-9938-7852
Michael P A DaviesDepartment of Molecular and Clinical Cancer Medicine, University of Liverpool. Roy Castle Lung Cancer Foundation, Liverpool, UK.
Jolanta LissowskaEpidemiology Unit, Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Beata ŚwiątkowskaHealth Capital School; Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland.
John McLaughlinDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Paul A DemersDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Vladimir BenckoInstitute of Hygiene and Epidemiology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Lenka ForetovaMasaryk Memorial Cancer Institute, Brno, Jihomoravský, Czech Republic.
Vladimir JanoutFaculty of Health Sciences, Palacky University, Olomouc, Czech Republic.
Tamás PándicsNational Public Health Center, Budapest, Hungary.
Eleonora FabianovaOccupational Health and Toxicology, Regional Authority of Public Health, Banska Bystrica, Slovakia.
Dana MatesNational Institute of Public Health, Bucharest, Romania.
Francesco ForastiereDepartment of Epidemiology, ASL Roma E, Rome, Italy.
Bas Bueno-de-MesquitaFormer senior scientist, Department for Determinants of Chronic Diseases, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Joachim SchüzInternational Agency for Research on Cancer, Lyon, France.
Kurt StraifInternational Agency for Research on Cancer, Lyon, France.ORCID 0000-0003-1402-2406
Ann OlssonInternational Agency for Research on Cancer, Lyon, France olssona@iarc.fr.ORCID 0000-0001-6498-2259
Centre international de recherche sur le cancer · FRInstitute for Prevention and Occupational Medicine · DEUniversity of Turin · ITUtrecht University · NL3M (United States) · USChinese University of Hong Kong · HKInserm · FRKarolinska Institutet · SENational Institutes of Health · USUniversité de Montréal · CAAmt für Umwelt · CHASL Roma · ITCenter for Environmental Health · USCharles University · CZFaculty of Public Health · GBFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITInstitut für Medizinische Informatik, Biometrie und Epidemiologie · DELeibniz Institute for Prevention Research and Epidemiology - BIPS · DELondon School of Hygiene & Tropical Medicine · GBMasaryk Memorial Cancer Institute · CZ

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectivesWe evaluated the risk of lung cancer associated with ever working as a painter, duration of employment and type of painter by histological subtype as well as joint effects with smoking, within the SYNERGY project.

methodsData were pooled from 16 participating case-control studies conducted internationally. Detailed individual occupational and smoking histories were available for 19 369 lung cancer cases (684 ever employed as painters) and 23 674 age-matched and sex-matched controls (532 painters). Multivariable unconditional logistic regression models were adjusted for age, sex, centre, cigarette pack-years, time-since-smoking cessation and lifetime work in other jobs that entailed exposure to lung carcinogens.

resultsEver having worked as a painter was associated with an increased risk of lung cancer in men (OR 1.30; 95% CI 1.13 to 1.50). The association was strongest for construction and repair painters and the risk was elevated for all histological subtypes, although more evident for small cell and squamous cell lung cancer than for adenocarcinoma and large cell carcinoma. There was evidence of interaction on the additive scale between smoking and employment as a painter (relative excess risk due to interaction >0).

conclusionsOur results by type/industry of painter may aid future identification of causative agents or exposure scenarios to develop evidence-based practices for reducing harmful exposures in painters.

Indexed as

AdultAgedAged, 80 and overCase-Control StudiesFemaleHumansLung NeoplasmsMaleMiddle AgedOccupational DiseasesOccupational ExposurePaintSex FactorsSmokingcancerepidemiologypainterssmoking

Identifiers

PMID33115922
PMCPMC7958079
OpenAlexW3095194243

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.