Evidence map›Paper›PMID 33115878›Full record

ArticleJournal of virology2020

Control of Archetype BK Polyomavirus MicroRNA Expression.

Wei Zou, Gau Shoua Vue, Benedetta Assetta, Heather Manza, Walter J Atwood, Michael J Imperiale

Abstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Biology of Polyomavirus miRNA.Frontiers in microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei ZouDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.
Gau Shoua VueDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.
Benedetta AssettaDepartment of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA.
Heather ManzaDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.
Walter J AtwoodDepartment of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA.ORCID 0000-0002-3763-9073
Michael J ImperialeDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA imperiale@umich.edu.ORCID 0000-0003-1218-6458

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Eric R. Fearon · 1988 to 2026
$178.2M
SYNTHETIC CHEMISTRY COREP01NS065719 · NINDS · BROWN UNIVERSITY · PI GEE, GRETCHEN VOGEL · 2009 to 2018
$12.3M
Virus-Host Cell Interactions in AIDS-Associated PMLR01NS043097 · NINDS · BROWN UNIVERSITY · PI ATWOOD, WALTER J · 2002 to 2020
$6.1M
Progressive Multifocal Leukoenephalopathy: Endemic Viruses and Lethal Brain DiseaseR35NS116836 · NINDS · BROWN UNIVERSITY · PI Walter J Atwood · 2020 to 2026
$5.7M
Parameters Governing Kidney Cell Infection with BKVR01AI060584 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI IMPERIALE, MICHAEL J. · 2004 to 2020
$4.8M
NCI NIH HHS P30 CA046592NIAID NIH HHS R01 AI060584NINDS NIH HHS P01 NS065719NINDS NIH HHS R01 NS043097NINDS NIH HHS R35 NS116836
6 · The paper itself

Abstract

BK polyomavirus (BKPyV) is a ubiquitous human pathogen, with over 80% of adults worldwide being persistently infected. BKPyV infection is usually asymptomatic in healthy people; however, it causes polyomavirus-associated nephropathy in renal transplant patients and hemorrhagic cystitis in bone marrow transplant patients. BKPyV has a circular, double-stranded DNA genome that is divided genetically into three parts: an early region, a late region, and a noncoding control region (NCCR). The NCCR contains the viral DNA replication origin and

Indexed as

Gene Expression Regulation, ViralBK VirusGenome, ViralHumansIntronsMicroRNAsRegulatory Sequences, Nucleic AcidRNA, MessengerRNA Splice SitesRNA SplicingRNA, ViralTranscription, GeneticMicroRNAsRNA, MessengerRNA Splice SitesRNA, ViralBKPyVmiRNApolyomavirusRNA splicing

Identifiers

PMID33115878
PMCPMC7944457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.