ArticleJournal of virology2021
Marek's Disease Virus Requires Both Copies of the Inverted Repeat Regions for Efficient
Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 17 citations in OpenAlex.
- Two distinct polymorphisms in the basic region of Meq protein of marek's disease virus alter pathological progression and clinical manifestations.Virology journal · 2025Article
- Article
- Role of the multiple telomeric repeat arrays in integration, persistence, and efficacy of the commercial CVI988 vaccine.mSphere · 2025Article
- Telomeric repeats in the commercial SB-1 vaccine facilitate viral integration and contribute to vaccine efficacy.NPJ vaccines · 2024Article
- Impact of viral telomeric repeat sequences on herpesvirus vector vaccine integration and persistence.PLoS pathogens · 2024Article
- Survey of Animal Neoplastic Cases Diagnosed in Nigerian Veterinary Teaching Hospitals, 2000-2017.Veterinary sciences · 2024Article
- LORF9 of Marek's disease virus is involved in the early cytolytic replication of B lymphocytes and can act as a target for gene deletion vaccine development.Journal of virology · 2023Article
- Systematic identification and characterization of repeat sequences in African swine fever virus genomes.Veterinary research · 2022Article
- In vivo imaging reveals novel replication sites of a highly oncogenic avian herpesvirus in chickens.PLoS pathogens · 2022Article
- The Diverse Major Histocompatibility Complex Haplotypes of a Common Commercial Chicken Line and Their Effect on Marek's Disease Virus Pathogenesis and Tumorigenesis.Frontiers in immunology · 2022Article
- Inverted repeats in coronavirus SARS-CoV-2 genome manifest the evolution events.Journal of theoretical biology · 2021Article
- A Cell Culture System to Investigate Marek's Disease Virus Integration into Host Chromosomes.Microorganisms · 2021Article
- The Marek's Disease Virus Unique Gene MDV082 Is Dispensable for Virus Replication but Contributes to a Rapid Disease Onset.Journal of virology · 2021Article
- Characterization of a Novel Viral Interleukin 8 (vIL-8) Splice Variant Encoded by Marek's Disease Virus.Microorganisms · 2021Article
- Latest Insights into Unique Open Reading Frames Encoded by Unique Long (UL) and Short (US) Regions of Marek's Disease Virus.Viruses · 2021Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Marek's disease virus (MDV) is an oncogenic alphaherpesvirus of chickens. The MDV genome consists of two unique regions that are both flanked by inverted repeat regions. These repeats harbor several genes involved in virus replication and pathogenesis, but it remains unclear why MDV and other herpesviruses harbor these large sequence duplications. In this study, we set to determine if both copies of these repeat regions are required for MDV replication and pathogenesis. Our results demonstrate that MDV mutants lacking the entire internal repeat region (ΔIR
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