Evidence map›Paper›PMID 33115874›Full record

ArticleJournal of virology2020

Relationships between Neutralization, Binding, and ADCC of Broadly Neutralizing Antibodies against Reservoir HIV.

Yanqin Ren, Maria Korom, Adam R Ward, Ronald Truong, Dora Chan, Szu-Han Huang, Colin M Kovacs, Erika Benko, Jeffrey T Safrit, John Lee and 3 more

Abstract readLetter
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. T-Follicular-Like CD8Frontiers in immunology · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yanqin RenDivision of Infectious Diseases, Weill Cornell Medicine, New York, New York, USA.
Maria KoromDept. of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA.
Adam R WardDivision of Infectious Diseases, Weill Cornell Medicine, New York, New York, USA.
Ronald TruongDept. of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA.
Dora ChanDept. of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA.
Szu-Han HuangDivision of Infectious Diseases, Weill Cornell Medicine, New York, New York, USA.
Colin M KovacsMaple Leaf Medical Clinic, Toronto, Ontario, Canada.
Erika BenkoMaple Leaf Medical Clinic, Toronto, Ontario, Canada.
Jeffrey T SafritNantBioScience Inc., NantKwest LLC, Culver City, California, USA.
John LeeNantBioScience Inc., NantKwest LLC, Culver City, California, USA.
Hermes GarbánNantWorks, LLC, Culver City, California, USA.
Rebecca LynchDept. of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA.
R Brad JonesDivision of Infectious Diseases, Weill Cornell Medicine, New York, New York, USA rbjones@med.cornell.edu.ORCID 0000-0003-4470-1231

Funding

BELIEVE: Bench to Bed Enhanced Lymphocyte Infusions to Engineer Viral EradicationUM1AI126617 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI JONES, R. BRAD, NIXON, DOUGLAS F · 2016 to 2020
$28.1M
Targeted delivery of cytopathicity enhancing agents, and co-ordination with shock and kill, to reduce HIV reservoirsR01AI147845 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI IRVINE, DARRELL J, JONES, R. BRAD · 2019 to 2023
$4.0M
CTL-Mediated Elimination of Replication Competent vs. Defective HIV Proviruses from Natural Latent Reservoirs: Roles of Antigen Specificity and Functional CharacteristicsR01AI131798 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI JONES, R. BRAD · 2017 to 2021
$2.1M
DETECTION OF HIV TARGETS BY GOLD NANOPARTICLE PROBESR01AI052764 · NIAID · NORTHWESTERN UNIVERSITY · PI WOLINSKY, STEVEN M · 2002 to 2004
$795k
Characterization of a Memory CD4+ T-cell Humanized Mouse Model for the Evaluation of Autologous Cell Therapies and Studies of HIV PersistenceR21AI152828 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI JONES, R. BRAD · 2020 to 2021
$466k
NIAID NIH HHS R01 AI052764NIAID NIH HHS R01 AI131798NIAID NIH HHS R01 AI147845NIAID NIH HHS R21 AI152828NIAID NIH HHS UM1 AI126617
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibody-Dependent Cell CytotoxicityBinding Sites, AntibodyBroadly Neutralizing AntibodiesCell LineHIVHIV AntibodiesHumansNeutralization TestsBroadly Neutralizing AntibodiesHIV Antibodiesantibody-dependent cellular cytotoxicityantibody neutralizationbroadly neutralizing antibodiesHIVHIV cure

Identifiers

PMID33115874
PMCPMC7944442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.