Evidence map›Paper›PMID 33115865›Full record

ReviewJournal of virology2020

Role of Inflammation in Virus Pathogenesis during Pregnancy.

Anna Chudnovets, Jin Liu, Harish Narasimhan, Yang Liu, Irina Burd

Open access · greenAbstract readReview
In one paragraph

Review in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Observational
  13. Review
  14. Article
  15. Article
  16. The plasma virome in longitudinal samples from pregnant patients.Frontiers in cellular and infection microbiology · 2023
    Article
  17. Greater Risk of Pregnancy Complications for Female Surgeons: A Cross-Sectional Electronic Survey.International journal of environmental research and public health · 2022
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anna ChudnovetsIntegrated Research Center for Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jin LiuIntegrated Research Center for Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Harish NarasimhanW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Yang LiuIntegrated Research Center for Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Irina BurdIntegrated Research Center for Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA iburd@jhmi.edu.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI S. Ali Fatemi, Bradley L Schlaggar · 2020 to 2026
$9.9M
IL-1β regulation of Zika-mediated adverse perinatal outcomesR01HD097608 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI BURD, IRINA, KLEIN, SABRA L. · 2018 to 2022
$2.9M
Placental determinants of neonatal immune function in maternal HIV infectionR21HD099000 · NICHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI BURD, IRINA, MATHAD, JYOTI S · 2019 to 2020
$482k
NICHD NIH HHS P50 HD103538NICHD NIH HHS R01 HD097608NICHD NIH HHS R21 HD099000
6 · The paper itself

Abstract

Viral infections during pregnancy lead to a spectrum of maternal and fetal outcomes, ranging from asymptomatic disease to more critical conditions presenting with severe maternal morbidity, stillbirth, preterm birth, intrauterine growth restriction, and fetal congenital anomalies, either apparent at birth or later in life. In this article, we review the pathogenesis of several viral infections that are particularly relevant in the context of pregnancy and intrauterine inflammation. Understanding the diverse mechanisms employed by viral pathogens as well as the repertoire of immune responses induced in the mother may help to establish novel therapeutic options to attenuate changes in the maternal-fetal interface and prevent adverse pregnancy outcomes.

Indexed as

FemaleHumansInfant, NewbornInflammationPlacentaPregnancyPregnancy Complications, InfectiousPregnancy OutcomeVirus DiseasesVirusesinflammationpregnancyviral infection

Identifiers

PMID33115865
PMCPMC7944452
OpenAlexW3096658018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.