Evidence map›Paper›PMID 33115839›Full record

ArticlemSphere2020

Genetic Determinants of Resistance to Extended-Spectrum Cephalosporin and Fluoroquinolone in Escherichia coli Isolated from Diseased Pigs in the United States.

Shivdeep Singh Hayer, Seunghyun Lim, Samuel Hong, Ehud Elnekave, Timothy Johnson, Albert Rovira, Fabio Vannucci, Jonathan B Clayton, Andres Perez, Julio Alvarez

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. ESBL-producingOne health (Amsterdam, Netherlands) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Flumequine, a fluoroquinolone in disguise.npj antimicrobials and resistance · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Antimicrobial agents and chemotherapy · 2024
    Review
  17. One health transmission of fluoroquinolone-resistantOne health (Amsterdam, Netherlands) · 2023
    Article
  18. Antimicrobial Resistance in CommensalAntibiotics (Basel, Switzerland) · 2023
    Review
  19. Article
  20. Genomic Characterization of FecalPathogens (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Shivdeep Singh HayerDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.
Seunghyun LimDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.
Samuel HongDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.
Ehud ElnekaveDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.
Timothy JohnsonDepartment of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.
Albert RoviraDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.
Fabio VannucciDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.
Jonathan B ClaytonDepartment of Biology, University of Nebraska at Omaha, Omaha, Nebraska, USA.
Andres PerezDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.
Julio AlvarezDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA jalvarez@visavet.ucm.es.ORCID 0000-0002-8999-9417
University of Minnesota · USUniversidad Complutense de Madrid · ESUniversity of Nebraska at Omaha · USUniversity of Nebraska–Lincoln · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluoroquinolones and cephalosporins are critically important antimicrobial classes for both human and veterinary medicine. We previously found a drastic increase in enrofloxacin resistance in clinical

Indexed as

AnimalsAnti-Bacterial AgentsCephalosporinsDNA, BacterialDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli InfectionsFluoroquinolonesGlobal HealthMicrobial Sensitivity TestsPlasmidsSwineUnited StatesAnti-Bacterial AgentsCephalosporinsDNA, BacterialFluoroquinolonesantimicrobial resistancecephalosporinepidemic plasmidsESBLsfluoroquinolonehigh-risk cloneslong-read sequencingPacBioplasmidsPMQRswineUSAWGS

Identifiers

PMID33115839
PMCPMC8534314
OpenAlexW3096314717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.