Evidence map›Paper›PMID 33115740›Full record

ArticleScience advances2020

The inositol pyrophosphate 5-InsP

Alfred C Chin, Zhe Gao, Andrew M Riley, David Furkert, Christopher Wittwer, Amit Dutta, Tomas Rojas, Evan R Semenza, Robin A Felder, Jennifer L Pluznick and 5 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  5. NaInternational journal of molecular sciences · 2024
    Review
  6. Review
  7. Article
  8. Synthesis and biological evaluation of flavonoid-based IP6K2 inhibitors.Journal of enzyme inhibition and medicinal chemistry · 2023
    Article
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 5 countries.

Alfred C ChinThe Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-6383-2689
Zhe GaoTianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin, China.ORCID 0000-0002-7186-3837
Andrew M RileyMedicinal Chemistry and Drug Discovery, Department of Pharmacology, University of Oxford, Oxford, UK.ORCID 0000-0001-9003-3540
David FurkertLeibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany.ORCID 0000-0002-6145-5397
Christopher WittwerInstitute of Organic Chemistry and CIBSS-Centre for Integrative Biological Signalling Studies, University of Freiburg, D-79104 Freiburg, Germany.ORCID 0000-0003-2393-0190
Amit DuttaInstitute of Organic Chemistry and CIBSS-Centre for Integrative Biological Signalling Studies, University of Freiburg, D-79104 Freiburg, Germany.
Tomas RojasThe Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-5154-3625
Evan R SemenzaThe Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-3494-6542
Robin A FelderDepartment of Pathology, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0003-2797-4289
Jennifer L PluznickDepartment of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-3621-2665
Henning J JessenInstitute of Organic Chemistry and CIBSS-Centre for Integrative Biological Signalling Studies, University of Freiburg, D-79104 Freiburg, Germany.ORCID 0000-0002-1025-9484
Dorothea FiedlerLeibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany.
Barry V L PotterMedicinal Chemistry and Drug Discovery, Department of Pharmacology, University of Oxford, Oxford, UK.ORCID 0000-0003-3255-9135
Solomon H SnyderThe Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA. ssnyder@jhmi.edu chenglaifu@tmu.edu.cn.ORCID 0000-0002-6818-7022
Chenglai FuTianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin, China. ssnyder@jhmi.edu chenglaifu@tmu.edu.cn.ORCID 0000-0003-4300-9948
Johns Hopkins University · USUniversity of Freiburg · DELeibniz-Forschungsinstitut für Molekulare Pharmakologie · DETianjin Medical University · CNUniversity of Oxford · GBUniversity of Virginia · US

Funding

NEUROCHEMICAL ACTIONS OF PSYCHOTROPIC DRUGSR37MH018501 · NIMH · JOHNS HOPKINS UNIVERSITY · PI SNYDER, SOLOMON H. · 1990 to 2009
$11.5M
NEUROCHEMICAL ACTIONS OF PSYCHOTROPIC DRUGSR01MH018501 · NIMH · JOHNS HOPKINS UNIVERSITY · PI SNYDER, SOLOMON H. · 1985 to 2019
$10.8M
Microbial Short Chain Fatty Acids and Blood Pressure RegulationR01HL128512 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI PLUZNICK, JENNIFER L · 2016 to 2020
$2.0M
Uncovering the Functional Role of Olfr78 in Blood Pressure RegulationR01DK107726 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI PLUZNICK, JENNIFER L · 2016 to 2020
$1.8M
NHLBI NIH HHS R01 HL128512NIDDK NIH HHS R01 DK107726NIMH NIH HHS R01 MH018501NIMH NIH HHS R37 MH018501Wellcome Trust
6 · The paper itself

Abstract

Sodium/potassium-transporting adenosine triphosphatase (Na

Identifiers

PMID33115740
PMCPMC7608788
OpenAlexW3082060899

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.