Evidence map›Paper›PMID 33115717›Full record

ArticleBMJ (Clinical research ed.)2020

Adversity in childhood is linked to mental and physical health throughout life.

Charles A Nelson, Richard David Scott, Zulfiqar A Bhutta, Nadine Burke Harris, Andrea Danese, Muthanna Samara

Registry-linked trialAbstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06821035 (Teaching Youth & Families Self-Regulation Skills to Disrupt the Impact of Adverse Childhood Experiences), which is not on this map. Cited by 354 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
354citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06821035 narecruitingnot on this mapstarted 2025, after this paper: background citation

Teaching Youth & Families Self-Regulation Skills to Disrupt the Impact of Adverse Childhood Experiences: Preventing Substance Use in Adversity- Impacted Youth

TypeinterventionalSponsorUniversity of California, IrvineRan2025 to 2028Enrolled210ConditionsAdverse Childhood Experiences, Family FunctioningArmsGarnering Resilience in Traumatized youth and families (GRIT), Digital Citizenship Curriculum (DCC)
3 · Its place in the literature

Who cites it

354 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  7. Adverse childhood events and mental health problems in cancer survivors: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  19. Adverse Childhood Experiences, Depression and Subjective Cognitive Decline by Gender: A Moderated Mediation Analysis.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
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  20. Observational

294 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Charles A Nelson
Richard David ScottDepartment of Pediatrics, Boston Children's Hospital and Harvard Medical School, Harvard Graduate School of Education, Boston, MA, USA.
Zulfiqar A BhuttaCentre for Global Child Health, Hospital for Sick Children, Toronto, Canada.
Nadine Burke HarrisState of California, CA, USA.
Andrea DaneseInstitute of Psychiatry, Psychology and Neuroscience, King's College London and the National and Specialist CAMHS Clinic for Trauma, Anxiety, and Depression, South London and Maudsley NHS Foundation Trust, London, UK.
Muthanna SamaraDepartment of Psychology, Kingston University London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adverse Childhood ExperiencesHealth StatusLife Change EventsMental HealthChildChild, PreschoolExposure to ViolenceHumansInfantPsychological TraumaStress, Psychological

Identifiers

PMID33115717
PMCPMC7592151

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.