Evidence map›Paper›PMID 33115698›Full record

ArticleInternational journal of hygiene and environmental health2021

Seasonality of drinking water sources and the impact of drinking water source on enteric infections among children in Limpopo, South Africa.

Kathy H Nguyen, Darwin J Operario, Mzwakhe E Nyathi, Courtney L Hill, James A Smith, Richard L Guerrant, Amidou Samie, Rebecca A Dillingham, Pascal O Bessong, Elizabeth T Rogawski McQuade

Open access · hybridAbstract read
In one paragraph

Article in International journal of hygiene and environmental health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 35 citations in OpenAlex.

  1. Waterborne diseases and climate change.Nature reviews. Microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Kathy H NguyenDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA, 22908, USA.
Darwin J OperarioDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, 22908, USA.
Mzwakhe E NyathiDepartment of Animal Science, University of Venda, Limpopo Province, Thohoyandou, 0950, South Africa.
Courtney L HillDepartment of Engineering Systems and Environment, University of Virginia, Charlottesville, VA, 22904, USA.
James A SmithDepartment of Engineering Systems and Environment, University of Virginia, Charlottesville, VA, 22904, USA.
Richard L GuerrantDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, 22908, USA.
Amidou SamieDepartment of Microbiology, University of Venda, Limpopo Province, Thohoyandou, 0950, South Africa.
Rebecca A DillinghamDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, 22908, USA.
Pascal O BessongDepartment of Microbiology, University of Venda, Limpopo Province, Thohoyandou, 0950, South Africa.
Elizabeth T Rogawski McQuadeDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA, 22908, USA; Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, 22908, USA. Electronic address: etr5m@virginia.edu.
University of Virginia · USUniversity of Venda · ZAEngineering Systems (United States) · USUniversity of Virginia Health System · US

Funding

The Water and Health in Limpopo Innovations Fellowship ProgramD43TW009359 · FIC · UNIVERSITY OF VIRGINIA · PI GUERRANT, RICHARD L · 2012 to 2016
$1.7M
UVa MHIRT: Training Future Leaders to Address Global Rural Health DisparitiesT37MD008659 · NIMHD · UNIVERSITY OF VIRGINIA · PI DILLINGHAM, REBECCA A., KOOLS, SUSAN MCEVILLY · 2014 to 2018
$1.3M
Translation of epidemiologic findings in enteric disease to public health actionK01AI130326 · NIAID · UNIVERSITY OF VIRGINIA · PI ROGAWSKI MCQUADE, ELIZABETH TACKET · 2018 to 2022
$612k
FIC NIH HHS D43 TW009359NIAID NIH HHS K01 AI130326NIMHD NIH HHS T37 MD008659
6 · The paper itself

Abstract

Enteric infections and water-related illnesses are more frequent during times of relative water abundance, especially in regions that experience bimodal rainfall patterns. However, it is unclear how seasonal changes in water availability and drinking water source types affect enteric infections in young children. This study investigated seasonal shifts in primary drinking water source type and the effect of water source type on enteric pathogen prevalence in stool samples from 404 children below age 5 in rural communities in Limpopo Province, South Africa. From wet to dry season, 4.6% (n = 16) of households switched from a source with a higher risk of contamination to a source with lower risk, with the majority switching to municipal water during the dry season. In contrast, 2.6% (n = 9) of households switched from a source with a lower risk of contamination to a source with higher risk. 74.5% (n = 301) of the total households experienced interruptions in their water supply, regardless of source type. There were no significant differences in enteric pathogen prevalence between drinking water sources. Intermittent municipal water distribution and household water use and storage practices may have a larger impact on enteric infections than water source type. The limited differences in enteric pathogen prevalence in children by water source could also be due to other exposure pathways in addition to drinking water, for example through direct contact and food-borne transmission.

Indexed as

Drinking WaterChildChild, PreschoolHumansRural PopulationSouth AfricaWater MicrobiologyWater SupplyDrinking WaterAccessEnteric infectionPathogenSeasonalityWater qualityWater source

Identifiers

PMID33115698
PMCPMC7736504
OpenAlexW3093922371

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.