Evidence map›Paper›PMID 33115487›Full record

Trial reportJournal of neuroengineering and rehabilitation2020

Immersive Virtual Environments and Wearable Haptic Devices in rehabilitation of children with neuromotor impairments: a single-blind randomized controlled crossover pilot study.

Ilaria Bortone, Michele Barsotti, Daniele Leonardis, Alessandra Crecchi, Alessandra Tozzini, Luca Bonfiglio, Antonio Frisoli

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neuroengineering and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03353623 (A Randomized Controlled Single-Blind Crossover Trial on the Effects of Serious Games and Wearable Haptic Devices in the Rehabilitation of Children With Neuromotor Impairments), which is not on this map. Cited by 31 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03353623 nacompletednot on this map

A Randomized Controlled Single-Blind Crossover Trial on the Effects of Serious Games and Wearable Haptic Devices in the Rehabilitation of Children With Neuromotor Impairments

TypeinterventionalSponsorScuola Superiore di Studi Universitari e di Perfezionamento Sant'AnnaRan2017 to 2017Enrolled8ConditionsCerebral Palsy, DyspraxiaArmsSerious Game, Conventional Therapy
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. The use of virtual reality in the stimulation of manual function in children with cerebral palsy: a systematic review.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2023
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  10. Soft, Flexible, and Stretchable Platforms for Tissue-Interfaced Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ilaria BortoneInstitute of Clinical Physiology (IFC), National Research Council (CNR), Pisa, Italy. ilariabortone@gmail.com.ORCID 0000-0002-4767-5334
Michele BarsottiPERCRO Laboratory, Scuola Superiore Sant'Anna, Pisa, Italy.
Daniele LeonardisPERCRO Laboratory, Scuola Superiore Sant'Anna, Pisa, Italy.
Alessandra CrecchiUnit of Developmental Neurorehabilitation, Maternal and Child Department, Pisa University Hospital, Pisa, Italy.
Alessandra TozziniUnit of Developmental Neurorehabilitation, Maternal and Child Department, Pisa University Hospital, Pisa, Italy.
Luca BonfiglioUnit of Developmental Neurorehabilitation, Maternal and Child Department, Pisa University Hospital, Pisa, Italy.
Antonio FrisoliPERCRO Laboratory, Scuola Superiore Sant'Anna, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe past decade has seen the emergence of rehabilitation treatments using virtual reality. One of the advantages in using this technology is the potential to create positive motivation, by means of engaging environments and tasks shaped in the form of serious games. The aim of this study is to determine the efficacy of immersive Virtual Environments and weaRable hAptic devices (VERA) for rehabilitation of upper limb in children with Cerebral Palsy (CP) and Developmental Dyspraxia (DD).

methodsA two period cross-over design was adopted for determining the differences between the proposed therapy and a conventional treatment. Eight children were randomized into two groups: one group received the VERA treatment in the first period and the manual therapy in the second period, and viceversa for the other group. Children were assessed at the beginning and the end of each period through both the Nine Hole Peg Test (9-HPT, primary outcome) and Kinesiological Measurements obtained during the performing of similar tasks in a real setting scenario (secondary outcomes).

resultsAll subjects, not depending from which group they come from, significantly improved in both the performance of the 9-HPT and in the parameters of the kinesiological measurements (movement error and smoothness). No statistically significant differences have been found between the two groups.

conclusionsThese findings suggest that immersive VE and wearable haptic devices is a viable alternative to conventional therapy for improving upper extremity function in children with neuromotor impairments. Trial registration ClinicalTrials, NCT03353623. Registered 27 November 2017-Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT03353623.

Indexed as

Virtual RealityWearable Electronic DevicesCerebral PalsyChildCross-Over StudiesFemaleGait ApraxiaHumansMalePilot ProjectsSingle-Blind MethodUpper ExtremityHuman Motion AnalysisRehabilitationSerious gameTactile FeedbackVirtual reality

Identifiers

PMID33115487
PMCPMC7594483

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.