Evidence map›Paper›PMID 33115429›Full record

ReviewBMC infectious diseases2020

Unusual disseminated Talaromyces marneffei infection mimicking lymphoma in a non-immunosuppressed patient in East China: a case report and review of the literature.

Donghe Chen, Chengdong Chang, Ming Chen, Yafei Zhang, Xin Zhao, Tingting Zhang, Zhen Wang, Jing Yan, Huanyan Zhu, Lin Zheng and 1 more

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Clinical Features and Diagnostic Challenges ofInfection and drug resistance · 2026
    Article
  2. Article
  3. Review
  4. Infection and drug resistance · 2025
    Article
  5. Disseminated CombinedInfection and drug resistance · 2024
    Article
  6. Article
  7. HIV-Negative Case ofInfection and drug resistance · 2024
    Article
  8. Review
  9. Talaromycosis from Wuhan: two-case report and literature review.Frontiers in cellular and infection microbiology · 2024
    Review
  10. Article
  11. Article
  12. CT findings ofFrontiers in medicine · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Donghe ChenPET Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P.R. China.
Chengdong ChangDepartment of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P.R. China.
Ming ChenBGI Genomics, Shenzhen, Guangdong, 518083, P.R. China.
Yafei ZhangPET Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P.R. China.
Xin ZhaoPET Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P.R. China.
Tingting ZhangPET Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P.R. China.
Zhen WangPET Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P.R. China.
Jing YanPET Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P.R. China.
Huanyan ZhuPET Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P.R. China.
Lin ZhengState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Hangzhou, Zhejiang, 310003, P.R. China.
Kui ZhaoPET Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, P.R. China. zhaokui0905@zju.edu.cn.
First Affiliated Hospital Zhejiang University · CNBGI GenomicsZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTalaromyces marneffei infection is an important opportunistic infection associated with acquired immune deficiency syndrome (AIDS). However, it is unusual in patients with non-AIDS and other non-immunosuppressed conditions. We report a case of delayed diagnosis of disseminated T. marneffei infection in non-AIDS, non-immunosuppressive and non-endemic conditions. CASE PRESENTATION: We describe a previously healthy 24-year-old man who complained of a 3-month history of intermittent diarrhea and a recent week of uncontrollable high fever. The HIV antibody test was negative. Enhanced abdominal computed tomography (CT) and integrated

conclusionsEarly diagnosis in HIV-negative patients who are otherwise not immunosuppressed and endemic poses a serious challenge. T. marneffei infection is an FDG-avid nonmalignant condition that may lead to false-positive FDG PET/CT scans. Nevertheless, integrated FDG PET/CT is necessary in patients with fever of unknown origin in the early period to perform earlier biopsy for histopathology and culture in highly avid sites and to avoid delays in diagnosis and treatment.

Indexed as

AIDS-Related Opportunistic InfectionsAmphotericin BAntifungal AgentsChinaDelayed DiagnosisDiagnosis, DifferentialFatal OutcomeFeverHigh-Throughput Nucleotide SequencingHIVHumansLiver Failure, AcuteLymphomaMaleMycosesPositron Emission Tomography Computed TomographyAmphotericin BAntifungal AgentsDelay in diagnosisFDG PET/CTNon-AIDS patientNon-immunosuppressed patientTalaromyces marneffei

Identifiers

PMID33115429
PMCPMC7594432
OpenAlexW3097539427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.