ArticleThe Journal of international medical research2020
Opioid-free anesthesia with a mixture of dexmedetomidine, ketamine, and lidocaine in one syringe for surgery in obese patients.
Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Comparison of End-tidal Sevoflurane Concentration Required for Optimal Depth of Anesthesia during Opioid-free General Anesthesia Using Intravenous Lignocaine versus Morphine.Annals of African medicine · 2026Trial
- Analgesic efficacy of the external oblique intercostal fascial plane block on postoperative acute pain in laparoscopic sleeve gastrectomy: a randomized controlled trial.Korean journal of anesthesiology · 2025Trial
- Intraoperative Non-Opiate Anesthesia for Patients Undergoing Arthroscopic Temporomandibular Joint Surgery: A Randomized Controlled Trial.Drug design, development and therapy · 2024Trial
- Physicochemical Stability of an S-Ketamine-Dexmedetomidine Anesthetic Mixture: An In Vitro Study.Cureus · 2026Article
- Intraoperative haemodynamic responses to opioid-free anaesthesia versus anaesthesia with fentanyl for laparoscopic cholecystectomy-a prospective observational pilot study.BMC anesthesiology · 2026Observational
- Comparison of Recurrence of Malignancy Following Two Opioid-free General Anesthesia Regimens versus Standard Care Using Opioids: A Retrospective Analysis.Annals of African medicine · 2026Article
- Opioid-Free Anesthesia for Upper Limb Surgery in Obese Patients as a Day Case Surgery: A Prospective Observational Study.Anesthesiology and pain medicine · 2024Article
- Article
- [Opioid-free anesthesia : Wrong track or meaningful exit from the era of opioid-based analgesia?]Die Anaesthesiologie · 2024Review
- Efficacy of intravenous dexmedetomidine-lignocaine infusion compared to morphine for intraoperative haemodynamic stability in modified radical mastectomy: A randomised controlled trial.Indian journal of anaesthesia · 2023Article
- Ketamine as a component of multimodal analgesia for pain management in bariatric surgery: A systematic review and meta-analysis of randomized controlled trials.Annals of medicine and surgery (2012) · 2022Review
- Is esketamine-based opioid-free anesthesia more superior for postoperative analgesia in obstructive sleep apnea patients undergoing bariatric surgery? A study protocol.Frontiers in medicine · 2022Article
- Injection of Lidocaine Alone versus Lidocaine plus Dexmedetomidine in Impacted Third Molar Extraction Surgery, a Double-Blind Randomized Control Trial for Postoperative Pain Evaluation.Pain research & management · 2021Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, there has been a trend toward minimizing opioid use in obese patients to prevent opioid-related postoperative complications. Moreover, the use of opioid-free anesthesia has received growing interest. This case series reports the use of simple opioid-free anesthesia consisting of a mixture of dexmedetomidine, ketamine, and lidocaine in an obese male patient undergoing laparoscopic bariatric surgery and an obese pregnant woman undergoing cesarean section. These cases indicate that opioid-free anesthesia can be safely administered to obese patients and provides effective pain control without any postoperative adverse outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.