Evidence map›Paper›PMID 33115300›Full record

Observational studyRenal failure2020

A visual risk assessment tool for acute kidney injury after intracranial aneurysm clipping surgery.

Pei Zhang, Chen Guan, Chenyu Li, Zhihui Zhu, Wei Zhang, Hong Luan, Bin Zhou, Xiaofei Man, Lin Che, Yanfei Wang and 4 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Renal failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Pei ZhangDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Chen GuanDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Chenyu LiDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhihui ZhuBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Wei ZhangDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Hong LuanDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Bin ZhouDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.ORCID https://orcid.org/0000-0002-2857-6648
Xiaofei ManDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Lin CheDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yanfei WangDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Long ZhaoDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Hui ZhangDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Congjuan LuoDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yan XuDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Qingdao University · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the study was to establish a predictive postoperative nomogram for acute kidney injury (AKI) after intracranial aneurysm clipping surgery, in order to early identify patients with high postoperative AKI risk.

methodsThis is a retrospective study, which included patients who underwent intracranial aneurysm clipping surgery. Multivariate logistic regression was employed to select confound factors that associated with AKI, then incorporated into the nomogram. The predictive accuracy of the model was assessed by concordance index (C-Index).

resultsA total of 365 patients after intracranial aneurysm clipping surgery were enrolled in the study eventually, of which 68 (18.63%) suffered postoperative AKI, and the incidence of stage 1, stage 2 and stage 3 were 92.65% (63/68), 5.88% (4/68), and 1.47% (1/68), respectively. Univariate logistic regression revealed that high density lipoprotein (HDL), prothrombin time (PT), estimated glomerular filtration rate (eGFR), size of aneurysm ≥10 mm, and aneurysm ruptured before surgery were associated with AKI after surgery, while multivariate logistic regression showed same results as the size of aneurysm ≥10 mm and aneurysm ruptured were independent AKI risk factors. In addition, the nomogram demonstrated a good accuracy in estimating intracranial aneurysm clipping associated AKI, as a C-Index and a bootstrap-corrected one of 0.772 and 0.737, respectively. Moreover, calibration plots showed consistency with the actual presence of AKI.

conclusionThe novel nomogram model can serve as a promising predictive tool to improve the identification of AKI among those who underwent intracranial aneurysm clipping surgery.

Indexed as

NomogramsPostoperative ComplicationsAcute Kidney InjuryAgedFemaleGlomerular Filtration RateHumansIncidenceIntracranial AneurysmLogistic ModelsMaleMiddle AgedMultivariate AnalysisRetrospective StudiesRisk AssessmentRisk Factorsacute kidney injuryIntracranial aneurysm clipping surgerynomogrampredictive model

Identifiers

PMID33115300
PMCPMC7599021
OpenAlexW3097293223

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.